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Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice
المؤلفون المشاركون
Escoto, Jorge
Ramírez Durán, Ninfa
Valdés-Ramos, Roxana
Martínez-Carrillo, Beatríz E.
Rosales-Gómez, Cristian Angel
Reséndiz-Albor, Aldo Arturo
Mondragón-Velásquez, Talia
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-24
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Background.
The consumption of sweeteners has increased in recent years, being used to control body weight and blood glucose.
However, they can cause increased appetite, modification of immune function, and secretion of hormones in the GALT.
Objective.
To assess the effect of chronic sweetener consumption on glycaemia, cytokines, hormones, and GALT lymphocytes in CD1 mice.
Material and Methods.
72 CD1 mice divided into 3 groups were used: (a) baseline, (b) middle, and (c) final.
Groups (b) and (c) were divided into 4 subgroups: (i) Control, (ii) Sucrose, (iii) Sucralose, and (iv) Stevia.
The following were determined: body weight, hormones (GIP, insulin, and leptin), lymphocytes CD3+T cells and CD19+B cells, IgA+ plasma cells, and cytokines (IL-4, IL-5, IFN-γ, and TNF-α).
Results.
Sucralose reduces secretion of GIP and glycaemia but does not modify insulin concentration, increases body weight, and reduces food intake.
Stevia increases the secretion of GIP, insulin, leptin, body weight, and glycaemia but keeps food consumption normal.
Sucralose and Stevia showed a higher percentage of CD3+T cells, CD19+B cells, and IgA+ plasma cells in Peyer’s patches, but only Stevia in lamina propria.
Conclusion.
Sweeteners modulate the hormonal response of cytokines and the proliferation of lymphocytes in the intestinal mucosa.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rosales-Gómez, Cristian Angel& Martínez-Carrillo, Beatríz E.& Reséndiz-Albor, Aldo Arturo& Ramírez Durán, Ninfa& Valdés-Ramos, Roxana& Mondragón-Velásquez, Talia…[et al.]. 2018. Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice. BioMed Research International،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1124251
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rosales-Gómez, Cristian Angel…[et al.]. Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice. BioMed Research International No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1124251
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rosales-Gómez, Cristian Angel& Martínez-Carrillo, Beatríz E.& Reséndiz-Albor, Aldo Arturo& Ramírez Durán, Ninfa& Valdés-Ramos, Roxana& Mondragón-Velásquez, Talia…[et al.]. Chronic Consumption of Sweeteners and Its Effect on Glycaemia, Cytokines, Hormones, and Lymphocytes of GALT in CD1 Mice. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1124251
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124251
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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