Associations of Serum Nitric Oxide with Vitamin D and Other Metabolic Factors in Apparently Healthy Adolescents
المؤلفون المشاركون
Alokail, Majed
Al-Daghri, Nasser M.
Bukhari, Ihtisham
Yakout, Sobhy M.
Khattak, Malak N. K.
Aziz, Ibrahim
Sabico, Shaun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Nitric oxide (NOx) is an important biomolecule which interacts with other molecules including 25(OH)D to mediate various metabolic pathways.
Interactions and associations of NOx with 25(OH)D have been well studied both in vitro and in vivo, yet associations in apparently healthy adolescents have never been studied.
Methods.
A total of 740 (245 boys and 495 girls) apparently healthy Saudi adolescents aged 10-17 years were included in this cross-sectional study, to determine the associations of NOx with 25(OH)D and other biomarkers in Saudi adolescents.
Serum NOx, 25(OH)D, and other biochemical and anthropometric parameters were measured following standard protocols and manufacturers’ guidelines.
Results.
NOx level was significantly higher in boys than girls (p<0.001).
In all subjects, NOx showed a significant inverse correlation with 25(OH)D.
After stratification according to sex however this significant association was observed only in boys and not in girls.
NOx was also significantly associated with BMI, serum triglycerides, and systolic blood pressure in all subjects.
Conclusion.
The significantly inverse association of NOx and 25(OH)D among apparently healthy adolescents is influenced by sex and further strengthens the extraskeletal role of 25(OH)D in maintaining endothelial homeostasis in this age group, particularly in boys.
Whether vitamin D correction can influence NOx production over time among adolescents remains to be proven.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Al-Daghri, Nasser M.& Bukhari, Ihtisham& Yakout, Sobhy M.& Sabico, Shaun& Khattak, Malak N. K.& Aziz, Ibrahim…[et al.]. 2018. Associations of Serum Nitric Oxide with Vitamin D and Other Metabolic Factors in Apparently Healthy Adolescents. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124358
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Al-Daghri, Nasser M.…[et al.]. Associations of Serum Nitric Oxide with Vitamin D and Other Metabolic Factors in Apparently Healthy Adolescents. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1124358
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Al-Daghri, Nasser M.& Bukhari, Ihtisham& Yakout, Sobhy M.& Sabico, Shaun& Khattak, Malak N. K.& Aziz, Ibrahim…[et al.]. Associations of Serum Nitric Oxide with Vitamin D and Other Metabolic Factors in Apparently Healthy Adolescents. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1124358
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124358
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر