A Novel and Convenient Method for the Preparation and Activation of PRP without Any Additives: Temperature Controlled PRP
المؤلفون المشاركون
Du, Lijuan
Miao, Yong
Li, Xin
Shi, Panli
Hu, Zhi-Qi
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-13
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Platelet rich plasma (PRP) is a concentrate of autologous platelets which contain enrichment growth factors (GFs).
However, the addition of exogenous anticoagulant and procoagulant may result in clinical side effects and raise the price of PRP.
Herein, we report a novel method named temperature controlled PRP (t-PRP), in which exogenous additives are dispensable in the preparation and activation process.
Human blood samples were processed by a two-step centrifugation process under hypothermic conditions (4°C) to obtain t-PRP and rewarming up to 37°C to activate t-PRP.
Contemporary PRP (c-PRP) was processed as the control.
t-PRP showed a physiological pH value between 7.46 and 7.48 and up to 6.58 ± 0.45-fold significantly higher platelet concentration than that of whole blood compared with c-PRP (4.06-fold) in the preparation process.
Meanwhile, t-PRP also maintained a stable GF level between plasma and PRP.
After activation, t-PRP demonstrated natural fiber scaffolding, which trapped more platelet and GFs, and exhibited a slow release and degradation rate of GFs.
In addition, t-PRP exhibited the function of promoting wound healing.
t-PRP is a novel and convenient method for the preparation and activation of PRP without any additives.
Compared to c-PRP, t-PRP reflects more physiologic characteristics while maintaining high quality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Du, Lijuan& Miao, Yong& Li, Xin& Shi, Panli& Hu, Zhi-Qi. 2018. A Novel and Convenient Method for the Preparation and Activation of PRP without Any Additives: Temperature Controlled PRP. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1124627
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Du, Lijuan…[et al.]. A Novel and Convenient Method for the Preparation and Activation of PRP without Any Additives: Temperature Controlled PRP. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1124627
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Du, Lijuan& Miao, Yong& Li, Xin& Shi, Panli& Hu, Zhi-Qi. A Novel and Convenient Method for the Preparation and Activation of PRP without Any Additives: Temperature Controlled PRP. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1124627
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1124627
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر