Dittrichia viscosa L. Ethanolic Extract Based Ointment with Antiradical, Antioxidant, and Healing Wound Activities
المؤلفون المشاركون
Rhimi, Wafa
Hlel, Raoudha
Ben Salem, Issam
Boulila, Abdennacer
Rejeb, Ahmed
Saidi, Mouldi
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-22
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Dittrichia viscosa which belongs to the Asteraceae family is frequently used to treat hematomas and skin disorders in Mediterranean herbal medicine.
This study aims to validate its antioxidant effects and its potential on healing wounds.
The ethanolic extract of D.
viscosa leaves was formulated as 2.5% and 5% (w/w) in ointment bases on the beeswax and sesame oil.
During this study, the ethanolic D.
viscosa extract, ointments containing 2.5% and 5% of D.
viscosa extract, and the vehiculum were assessed for their total phenol content (TPC), caffeoylquinic acid content (CQC), and antioxidant activities using complementary methods (TAC, the DPPH, ABTS, FRAP, and the BCB).
The effects on wound healing of obtained ointments were evaluated by excision of the wound in a mice model for 12 days.
Subsequently, the excised wound areas were measured at the 3rd, 9th, and 12th days.
The skin tissues were isolated for histological studies.
The ointments containing D.
viscosa extract (2.5%, 5%) possessed a considerable TPC, CQC, radical scavenging potential, and antioxidant activities compared to the vehiculum.
Treated animals with ointments containing D.
viscosa extract at 2.5% and 5% showed almost and totally healed wounds compared to the vehiculum and control groups, evidenced by good skin regeneration and reepithelialization.
The present work showed the role of D.
viscosa antioxidants exerted by its polyphenolic compounds, in particular, caffeoylquinic acids, in enhancing wound healing.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rhimi, Wafa& Hlel, Raoudha& Ben Salem, Issam& Boulila, Abdennacer& Rejeb, Ahmed& Saidi, Mouldi. 2019. Dittrichia viscosa L. Ethanolic Extract Based Ointment with Antiradical, Antioxidant, and Healing Wound Activities. BioMed Research International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1125121
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rhimi, Wafa…[et al.]. Dittrichia viscosa L. Ethanolic Extract Based Ointment with Antiradical, Antioxidant, and Healing Wound Activities. BioMed Research International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1125121
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rhimi, Wafa& Hlel, Raoudha& Ben Salem, Issam& Boulila, Abdennacer& Rejeb, Ahmed& Saidi, Mouldi. Dittrichia viscosa L. Ethanolic Extract Based Ointment with Antiradical, Antioxidant, and Healing Wound Activities. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1125121
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125121
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر