Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco
المؤلفون المشاركون
Leouifoudi, Inass
Zyad, Abdelmajid
Tilaoui, Mounir
Jaafari, Abdeslam
Oukerrou, Moulay Ali
Mouse, Hassan Ait
المصدر
Advances in Pharmacological and Pharmaceutical Sciences
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-12
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The aim of this work is to investigate the in vitro cytotoxic and antibacterial effects of the essential oils of Aloysia citriodora Palau, harvested in different regions of Morocco.
The chemical profile was established using gas chromatography-mass spectrometry analysis.
The cytotoxic activity against P815, MCF7, and VERO cell lines as well as the normal human peripheral blood mononuclear cells (PBMCs) was evaluated using the MTT assay.
Standard, ATCC, strains of bacteria (Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa) were cultivated in Muller Hinton media.
Then, agar disc diffusion, minimum inhibitory concentrations (MICs), and minimal bactericidal concentrations (MBCs) were determined using microdilution method.
The essential oils obtained were predominantly composed of β-spathulenol (15.61%), Ar-curcumene (14.15%), trans-caryophyllene oxide (14.14%), and neral (10.02%).
The results of the assays showed that the cytotoxic effect of the essential oil of A.
citriodora was high on P815 and moderate on MCF7 and on VERO cell lines.
However, no cytotoxic effect was observed on PBMCs.
On the other hand, essential oils showed a significant antimicrobial activity against both Gram-negative and Gram-positive bacteria.
MICs ranged between 2.84 and 8.37 mg/ml.
Essential oil of A.
citriodora leaves possesses significant antibacterial effect and cytotoxic activity against tumor cell lines.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oukerrou, Moulay Ali& Tilaoui, Mounir& Mouse, Hassan Ait& Leouifoudi, Inass& Jaafari, Abdeslam& Zyad, Abdelmajid. 2017. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oukerrou, Moulay Ali…[et al.]. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oukerrou, Moulay Ali& Tilaoui, Mounir& Mouse, Hassan Ait& Leouifoudi, Inass& Jaafari, Abdeslam& Zyad, Abdelmajid. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125429
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر