Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco
Joint Authors
Leouifoudi, Inass
Zyad, Abdelmajid
Tilaoui, Mounir
Jaafari, Abdeslam
Oukerrou, Moulay Ali
Mouse, Hassan Ait
Source
Advances in Pharmacological and Pharmaceutical Sciences
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of this work is to investigate the in vitro cytotoxic and antibacterial effects of the essential oils of Aloysia citriodora Palau, harvested in different regions of Morocco.
The chemical profile was established using gas chromatography-mass spectrometry analysis.
The cytotoxic activity against P815, MCF7, and VERO cell lines as well as the normal human peripheral blood mononuclear cells (PBMCs) was evaluated using the MTT assay.
Standard, ATCC, strains of bacteria (Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa) were cultivated in Muller Hinton media.
Then, agar disc diffusion, minimum inhibitory concentrations (MICs), and minimal bactericidal concentrations (MBCs) were determined using microdilution method.
The essential oils obtained were predominantly composed of β-spathulenol (15.61%), Ar-curcumene (14.15%), trans-caryophyllene oxide (14.14%), and neral (10.02%).
The results of the assays showed that the cytotoxic effect of the essential oil of A.
citriodora was high on P815 and moderate on MCF7 and on VERO cell lines.
However, no cytotoxic effect was observed on PBMCs.
On the other hand, essential oils showed a significant antimicrobial activity against both Gram-negative and Gram-positive bacteria.
MICs ranged between 2.84 and 8.37 mg/ml.
Essential oil of A.
citriodora leaves possesses significant antibacterial effect and cytotoxic activity against tumor cell lines.
American Psychological Association (APA)
Oukerrou, Moulay Ali& Tilaoui, Mounir& Mouse, Hassan Ait& Leouifoudi, Inass& Jaafari, Abdeslam& Zyad, Abdelmajid. 2017. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
Modern Language Association (MLA)
Oukerrou, Moulay Ali…[et al.]. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
American Medical Association (AMA)
Oukerrou, Moulay Ali& Tilaoui, Mounir& Mouse, Hassan Ait& Leouifoudi, Inass& Jaafari, Abdeslam& Zyad, Abdelmajid. Chemical Composition and Cytotoxic and Antibacterial Activities of the Essential Oil of Aloysia citriodora Palau Grown in Morocco. Advances in Pharmacological and Pharmaceutical Sciences. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1125429
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1125429