Serum Trace Elements Profile in Graves’ Disease Patients with or without Orbitopathy in Northeast China
المؤلفون المشاركون
Mao, Jinyuan
Xie, Xiaochen
Teng, Weiping
Guan, Haixia
Qin, Jing
Liu, Yongping
Li, Yushu
Peng, Shiqiao
Liu, Shanshan
Piao, Sichen
Shan, Zhongyan
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-10
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
The purpose of the present study was to investigate serum trace elements in Graves’ disease (GD) patients with or without orbitopathy in Northeast China.
Methods.
Patients with newly diagnosed Graves’ disease (HyGD) (n=66), GD patients with euthyroid status or subclinical thyroidism after treatment (EUGD) (n=55), GO patients with euthyroid status or subclinical thyroidism after treatment (GO) (n=57), and normal controls (NC) (n=66) were enrolled in this study.
Serum trace elements were measured with ICP-MS.
Results.
Serum selenium (Se) levels in EUGD group (median: 7.53 µg/dL), HyGD group (median: 6.76 µg/dL), and GO group (median: 7.40 µg/dL) were significantly lower than those in NC group (median: 9.20 µg/dL, all P<0.01).
Serum copper (Cu) levels in GO group (median: 95.93 µg/dL) were significantly lower than those in the NC group (median: 113.59 µg/dL, P=0.015).
After being adjusted for multivariables, thyroid-specific antibodies grade was associated with low Se levels.
Hyperthyroidism and thyroid-specific antibodies grade were associated with high Cu levels.
In addition, orbitopathy was associated with low Cu levels.
Conclusions.
Thyroid autoimmunity was associated with low Se levels.
Hyperthyroidism and thyroid autoimmunity may be associated with relatively high serum Cu levels.
Alternatively, ophthalmopathy may be related to low serum Cu levels.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Yongping& Liu, Shanshan& Mao, Jinyuan& Piao, Sichen& Qin, Jing& Peng, Shiqiao…[et al.]. 2018. Serum Trace Elements Profile in Graves’ Disease Patients with or without Orbitopathy in Northeast China. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1125573
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Yongping…[et al.]. Serum Trace Elements Profile in Graves’ Disease Patients with or without Orbitopathy in Northeast China. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1125573
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Yongping& Liu, Shanshan& Mao, Jinyuan& Piao, Sichen& Qin, Jing& Peng, Shiqiao…[et al.]. Serum Trace Elements Profile in Graves’ Disease Patients with or without Orbitopathy in Northeast China. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1125573
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125573
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر