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Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane
المؤلفون المشاركون
Lee, Shyh-Yuan
Wu, Sheng-Chien
Chen, Hsuan
Tsai, Lo-Lin
Tzeng, Jy-Jiunn
Lin, Yuan-Min
Lin, Chih-Hsin
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-15
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The aim of this research is to synthesize polycaprolactone-based polyurethanes (PCL-based PUs) that can be further used for the fabrication of guided bone regeneration (GBR) membranes with higher tensile strength and elongation at break than collagen and PTFE membranes.
The PCL-based PUs were prepared by the polymerization of polycaprolactone (PCL) diol with 1,6-hexamethylene diisocyanate (HDI) at different ratios using either polyethylene glycol (PEG) or ethylenediamine (EDA) as chain extenders.
The chemical, mechanical, and thermal properties of the synthesized polymers were determined using NMR, FTIR, GPC, DSC, and tensile tester.
The PCL and polyurethanes were fabricated as nanofiber membranes by electrospinning, and their mechanical properties and SEM morphology were also investigated.
In vitro tests, including WST-1 assay, SEM of cells, and phalloidin cytoskeleton staining, were also performed.
It was shown that electrospun membranes made of PCL and PCL-HDI-PEG (2 : 3 : 1) possessed tensile strength of 19.84 MPa and 11.72 MPa and elongation at break of 627% and 362%, respectively.
These numbers are equivalent or higher than most of the commercially available collagen and PTFE membrane.
As a result, these membranes may have potential for future GBR applications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Shyh-Yuan& Wu, Sheng-Chien& Chen, Hsuan& Tsai, Lo-Lin& Tzeng, Jy-Jiunn& Lin, Chih-Hsin…[et al.]. 2018. Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane. BioMed Research International،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1125721
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Shyh-Yuan…[et al.]. Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane. BioMed Research International No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1125721
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Shyh-Yuan& Wu, Sheng-Chien& Chen, Hsuan& Tsai, Lo-Lin& Tzeng, Jy-Jiunn& Lin, Chih-Hsin…[et al.]. Synthesis and Characterization of Polycaprolactone-Based Polyurethanes for the Fabrication of Elastic Guided Bone Regeneration Membrane. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1125721
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125721
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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