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Immunoglobulin E and G Levels in Predicting Minimal Change Disease before Renal Biopsy
المؤلفون المشاركون
Hsiao, Ching-Chung
Tu, Kun-Hua
Hsieh, Chun-Yih
Lee, Cheng-Chia
Chang, Chih-Hsiang
Fan, Pei-Chun
Tian, Ya-Chung
Fang, Ji-Tseng
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
The diagnosis of minimal change disease in adults relies mainly on renal biopsy, but this procedure is not without complications.
Despite the advancements in technique of percutaneous renal biopsy, biopsy-related complications still occur.
Bleeding is one of the major complications, which may lead to hemodynamic instability and, sometimes, even death.
Thus, we developed a model to predict MCD for high-risk patients unsuitable for renal biopsy.
Methods.
We enrolled 142 patients with nephrotic syndrome who received renal biopsy between October 2007 and April 2011 at one tertiary medical center in this study.
Demographic, clinical, and prebiopsy laboratory variables were retrospectively recorded and analyzed.
Results.
The overall prevalence of MCD was 26.8%.
Age, hemoglobin levels, 24-hour urine protein, immunoglobulin (Ig) G, and IgE differed significantly between the MCD and non-MCD groups.
Logistic regression analysis showed a significant increase in the risk of developing MCD as the number of Ig risk factors, namely, IgG < 450 mg/dl and IgE > 110 mg/dl, increased.
Having both risk factors significantly increased the chances of receiving a diagnosis of MCD (by 31.84-fold, P =.007) compared with having neither.
Combining the aforementioned clinical model and the 2 Ig risk factors was the best in predicting the diagnosis of MCD, with the area under a receiver-operating characteristic curve of 0.91.
Conclusions.
Combining clinical model and this 2 Ig risk factors provides physicians simple and valuable clinical markers to diagnose MCD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hsiao, Ching-Chung& Tu, Kun-Hua& Hsieh, Chun-Yih& Lee, Cheng-Chia& Chang, Chih-Hsiang& Fan, Pei-Chun…[et al.]. 2018. Immunoglobulin E and G Levels in Predicting Minimal Change Disease before Renal Biopsy. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1125844
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hsiao, Ching-Chung…[et al.]. Immunoglobulin E and G Levels in Predicting Minimal Change Disease before Renal Biopsy. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1125844
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hsiao, Ching-Chung& Tu, Kun-Hua& Hsieh, Chun-Yih& Lee, Cheng-Chia& Chang, Chih-Hsiang& Fan, Pei-Chun…[et al.]. Immunoglobulin E and G Levels in Predicting Minimal Change Disease before Renal Biopsy. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1125844
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1125844
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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