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Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions
المؤلفون المشاركون
Maioli, Margherita
Santaniello, Sara
Cruciani, Sara
Fadda, Angela
Sale, Luana
Sarais, Giorgia
Sanna, Daniele
Mulas, Maurizio
Ginesu, Giorgio Carlo
Cossu, Maria Laura
Serra, Pier Andrea
Ventura, Carlo
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-11
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Nutraceuticals present in food are molecules able to exert biological activity for the prevention and treatment of various diseases, in form of pharmaceutical preparations, such as capsules, cream, or pills.
Myrtus communis L.
is a spontaneous Mediterranean evergreen shrub, widely known for the liqueur obtained from its berries rich in phytochemicals such as tannins and flavonoids.
In the present study, we aimed to evaluate the properties of myrtle byproducts, residual of the industrial liqueur processing, in Adipose-derived stem cells (ADSCs) induced at oxidative stress by in vitro H2O2 treatment.
Cells were exposed for 12-24 and 48h at treatment with extracts and then senescence-induced.
ROS production was then determined.
The real-time PCR was performed to evaluate the expression of inflammatory cytokines and sirtuin-dependent epigenetic changes, as well the modifications in terms of stem cell pluripotency.
The β-galactosidase assay was conducted to analyze stem cell senescence after treatment.
Our results show that industrial myrtle byproducts retain a high antioxidant and antisenescence activity, protecting cells from oxidative stress damages.
The results obtained suggest that residues from myrtle liqueur production could be used as resource in formulation of food supplements or pharmaceutical preparations with antioxidant, antiaging, and anti-inflammatory activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cruciani, Sara& Santaniello, Sara& Fadda, Angela& Sale, Luana& Sarais, Giorgia& Sanna, Daniele…[et al.]. 2019. Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions. BioMed Research International،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1126128
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cruciani, Sara…[et al.]. Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions. BioMed Research International No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1126128
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cruciani, Sara& Santaniello, Sara& Fadda, Angela& Sale, Luana& Sarais, Giorgia& Sanna, Daniele…[et al.]. Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1126128
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126128
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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