Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study
المؤلفون المشاركون
Ji, Baolan
Zhang, Mei
Ban, Bo
Wang, Panpan
Shao, Qian
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
The aim of this study was to examine the relationship between insulin-like growth factor-1 (IGF-1) and serum uric acid (UA) in Chinese children and adolescents with idiopathic short stature (ISS).
Methods.
A cross-sectional study of 91 Chinese children and adolescents with ISS was performed.
Anthropometric measurements and biochemical parameters were tested.
The standard deviation score of IGF-1 (IGF-1 SDS) was calculated.
Results.
A univariate analysis displayed a significant positive correlation between IGF-1 SDS and UA (P=0.004).
In multivariate piecewise linear regression, the levels of IGF-1 SDS increased with the elevation of UA when UA was between 168 μmol/L and 301 μmol/L (β 0.010, 95% CI 0.004–0.017; P=0.002).
The levels of IGF-1 SDS decreased with the elevation of UA when UA was either less than 168 μmol/L (β −0.055, 95% CI −0.081–−0.028; P<0.001) or more than 301 μmol/L (β −0.005, 95% CI −0.013–0.002; P=0.174).
Conclusions.
This study demonstrated a nonlinear relationship between IGF-1 and UA levels in Chinese children and adolescents with ISS.
This finding suggests that either high or low levels of UA may have an adverse effect on IGF-1, whereas appropriate UA levels have a beneficial effect.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Panpan& Ji, Baolan& Shao, Qian& Zhang, Mei& Ban, Bo. 2018. Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126474
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Panpan…[et al.]. Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1126474
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Panpan& Ji, Baolan& Shao, Qian& Zhang, Mei& Ban, Bo. Association between Insulin-Like Growth Factor-1 and Uric Acid in Chinese Children and Adolescents with Idiopathic Short Stature: A Cross-Sectional Study. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1126474
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126474
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر