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Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy
المؤلفون المشاركون
Wang, Haiqing
Liu, Aixiang
Bo, Wentao
Feng, Xielin
Hu, Yong
Tian, Lang
Zhang, Hui
Tang, Xiaoli
Zhang, Lixia
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-02
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Several noninvasive models based on routine laboratory index have been developed to predict liver fibrosis.
Our aim is to discuss whether these indexes could predict prognosis in patients with hepatocellular carcinoma undergoing hepatectomy.
Methods.
This study retrospectively enrolled 788 consecutive hepatocellular carcinoma patients undergoing liver resection in the cohort.
Univariate and multivariate analysis were used to identify the risk factors of complications, survival, and disease-free survival.
Results.
Fibrosis-4 index had the best prediction ability for cirrhosis among other noninvasive models.
Both the univariate and multivariate analyses showed that fibrosis-4 was independent risk factor for survival and disease-free survival.
With the optimal cutoff value of 3.15, patients with fibrosis-4 ⩾3.15 had higher postoperative hepatic insufficiency (P=0.006) and worse survival than the fibrosis-4<3.15 group.
The corresponding 1-year, 3-year, and 5-year overall survival were 80.9%, 56.3%, and 44.6% in the High fibrosis-4 group and were 86.5%, 69.9%, and 63.2% in the Low fibrosis-4 group, respectively (P<0.001).
Worse disease-free survival was also observed in the fibrosis-4 ⩾3.15 group; the corresponding 1-year, 3-year, and 5-year disease-free survival were 74.9%, 45.3%, and 24.6% for the fibrosis-4 ⩾3.15 group and were 81.8%, 54.9%, and 34.4% for the fibrosis-4<3.15 group (P=0.009).
Conclusions.
Fibrosis-4 is useful for assessing the short-term and long-term results for hepatocellular carcinoma patients with liver resection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Haiqing& Liu, Aixiang& Bo, Wentao& Feng, Xielin& Hu, Yong& Tian, Lang…[et al.]. 2018. Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy. BioMed Research International،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126522
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Haiqing…[et al.]. Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy. BioMed Research International No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1126522
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Haiqing& Liu, Aixiang& Bo, Wentao& Feng, Xielin& Hu, Yong& Tian, Lang…[et al.]. Fibrosis-4 Model Influences Results of Patients with Hepatocellular Carcinoma Undergoing Hepatectomy. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1126522
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126522
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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