Precision Medicine in Targeted Therapies for Severe Asthma: Is There Any Place for “Omics” Technology?
المؤلفون المشاركون
Galeone, Carla
Facciolongo, Nicola
Scelfo, Chiara
Bertolini, Francesca
Caminati, Marco
Ruggiero, Patrizia
Menzella, Francesco
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-11
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
According to the current guidelines, severe asthma still represents a controversial topic in terms of definition and management.
The introduction of novel biological therapies as a treatment option for severe asthmatic patients paved the way to a personalized approach, which aims at matching the appropriate therapy with the different asthma phenotypes.
Traditional asthma phenotypes have been decomposing by an increasing number of asthma subclasses based on functional and physiopathological mechanisms.
This is possible thanks to the development and application of different omics technologies.
The new asthma classification patterns, particularly concerning severe asthma, include an increasing number of endotypes that have been identified using new omics technologies.
The identification of endotypes provides new opportunities for the management of asthma symptoms, but this implies that biological therapies which target inflammatory mediators in the frame of specific patterns of inflammation should be developed.
However, the pathway leading to a precision approach in asthma treatment is still at its beginning.
The aim of this review is providing a synthetic overview of the current asthma management, with a particular focus on severe asthma, in the light of phenotype and endotype approach, and summarizing the current knowledge about “omics” science and their therapeutic relevance in the field of bronchial asthma.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Galeone, Carla& Scelfo, Chiara& Bertolini, Francesca& Caminati, Marco& Ruggiero, Patrizia& Facciolongo, Nicola…[et al.]. 2018. Precision Medicine in Targeted Therapies for Severe Asthma: Is There Any Place for “Omics” Technology?. BioMed Research International،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1126809
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Galeone, Carla…[et al.]. Precision Medicine in Targeted Therapies for Severe Asthma: Is There Any Place for “Omics” Technology?. BioMed Research International No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1126809
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Galeone, Carla& Scelfo, Chiara& Bertolini, Francesca& Caminati, Marco& Ruggiero, Patrizia& Facciolongo, Nicola…[et al.]. Precision Medicine in Targeted Therapies for Severe Asthma: Is There Any Place for “Omics” Technology?. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1126809
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1126809
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر