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The Signaling Pathways Involved in the Antiatherosclerotic Effects Produced by Chinese Herbal Medicines
المؤلفون المشاركون
Lu, Li
Sun, Xiaodong
Qin, Yating
Guo, Xiaomei
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-13
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Cardiovascular diseases (CVDs) are considered to be the predominant cause of death in the world.
Chinese herb medicines (CHMs) have been widely used for the treatment of CVDs in Asian countries for thousands of years.
One reason of high efficacy of CHMs in treating CVDs is attributed to their inhibition in atherosclerosis (AS) development, a critical contributor to CVDs occurrence.
Cumulative studies have demonstrated that CHMs alleviate atherogenesis via mediating pathophysiologic events involved in AS.
However, there is deficiency in the summaries regarding antiatherogenic signal pathways regulated by CHMs.
In this review, we focus on the signal cascades by which herb medicines and relevant extractives, derivatives, and patents improve proatherogenic processes including endothelium dysfunction, lipid accumulation, and inflammation.
We mainly elaborate the CHMs-mediated signaling pathways in endothelial cells, macrophages, and vascular smooth muscle cells of each pathogenic event.
Moreover, we briefly describe the other AS-related factors such as thrombosis, autophagy, immune response, and noncoding RNAs and effects of CHMs on them in the way of cascade regulation, which is helpful to further illustrate the molecular mechanisms of AS initiation and progression and discover newly effective agents for AS management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Li& Sun, Xiaodong& Qin, Yating& Guo, Xiaomei. 2018. The Signaling Pathways Involved in the Antiatherosclerotic Effects Produced by Chinese Herbal Medicines. BioMed Research International،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1127260
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Li…[et al.]. The Signaling Pathways Involved in the Antiatherosclerotic Effects Produced by Chinese Herbal Medicines. BioMed Research International No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1127260
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Li& Sun, Xiaodong& Qin, Yating& Guo, Xiaomei. The Signaling Pathways Involved in the Antiatherosclerotic Effects Produced by Chinese Herbal Medicines. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1127260
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127260
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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