Combined Optimized Effect of a Highly Self-Organized Nanosubstrate and an Electric Field on Osteoblast Bone Cells Activity
المؤلفون المشاركون
Deligianni, Despina
Kostopoulos, V.
Portan, Diana V.
Papanicolaou, George C.
Psarras, Georgios C.
Tyllianakis, Minos
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The effect of an electric field within specific intensity limits on the activity of human cells has been previously investigated.
However, there are a considerable number of factors that influence the in vitro development of cell populations.
In biocompatibility studies, the nature of the substrate and its topography are decisive in osteoblasts bone cells development.
Further on, electrical field stimulation may activate biochemical paths that contribute to a faster, more effective self-adjustment and proliferation of specific cell types on various nanosubstrates.
Within the present research, an electrical stimulation device has been manufactured and optimum values of parameters that led to enhanced osteoblasts activity, with respect to the alkaline phosphatase and total protein levels, have been found.
Homogeneous electric field distribution induced by a highly organized titanium dioxide nanotubes substrate had an optimum effect on cell response.
Specific substrate topography in combination with appropriate electrical stimulation enhanced osteoblasts bone cells capacity to self-adjust the levels of their specific biomarkers.
The findings are of importance in the future design and development of new advanced orthopaedic materials for hard tissue replacement.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Portan, Diana V.& Deligianni, Despina& Papanicolaou, George C.& Kostopoulos, V.& Psarras, Georgios C.& Tyllianakis, Minos. 2019. Combined Optimized Effect of a Highly Self-Organized Nanosubstrate and an Electric Field on Osteoblast Bone Cells Activity. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1127397
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Portan, Diana V.…[et al.]. Combined Optimized Effect of a Highly Self-Organized Nanosubstrate and an Electric Field on Osteoblast Bone Cells Activity. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1127397
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Portan, Diana V.& Deligianni, Despina& Papanicolaou, George C.& Kostopoulos, V.& Psarras, Georgios C.& Tyllianakis, Minos. Combined Optimized Effect of a Highly Self-Organized Nanosubstrate and an Electric Field on Osteoblast Bone Cells Activity. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1127397
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127397
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر