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Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients
المؤلفون المشاركون
Lyra, Andre Castro
Santana, Genoile Oliveira
Silva, Juliana
Brito, Beatriz S.
Silva, Isaac Neri de N.
Nóbrega, Viviane G.
Silva, Maria Carolina S. M. da
Gomes, Hemerson Dyego de N.
Fortes, Flora Maria
Pimentel, Andrea M.
Mota, Jaciane
Almeida, Neogélia
Surlo, Valdiana C.
Rocha, Raquel
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
In inflammatory bowel disease (IBD) patients there are reports of the occurrence of hepatobiliary manifestations, so the aim of this study was to evaluate the hepatobiliary manifestations in patients with Crohn’s disease (CD) and ulcerative colitis (UC) from an IBD reference center.
Methods.
Cross-sectional study in an IBD reference center, with interviews and review of medical charts, between July 2015 and August 2016.
A questionnaire addressing epidemiological and clinical characteristics was used.
Results.
We interviewed 306 patients, and the majority had UC (53.9%) and were female (61.8%).
Hepatobiliary manifestations were observed in 60 (19.6%) patients with IBD.
In the greater part of the patients (56.7%) hepatobiliary disorders were detected after the diagnosis of IBD.
In UC (18.2%) patients, the hepatobiliary disorders identified were 11 (6.7%) non-alcoholic fatty liver disease, 9 (5.5%) cholelithiasis, 6 (3.6%) primary sclerosing cholangitis (PSC), 3 (1.8%) hepatotoxicity associated with azathioprine, 1 (0.6%) hepatitis B, and 1 (0.6%) hepatic fibrosis.
In CD (21.3%) patients, 11 (7.8%) had cholelithiasis, 11 (7.8%) non-alcoholic fatty liver disease, 4 (2.8%) PSC, 3 (2.1%) hepatotoxicity, 1 (0.7%) hepatitis B, (0.7%) hepatitis C, 1 (0.7%) alcoholic liver disease, and 1 (0.7%) autoimmune hepatitis (AIH).
There was one case of PSC/AIH overlap syndrome.
Conclusion.
The frequency of hepatobiliary disorders was similar in both forms of IBD in patients evaluated.
The most common nonspecific hepatobiliary manifestations in IBD patients were non-alcoholic liver disease and cholelithiasis.
The most common specific hepatobiliary disorder was PSC in patients with extensive UC or ileocolonic CD involvement; this was seen more frequently in male patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Silva, Juliana& Brito, Beatriz S.& Silva, Isaac Neri de N.& Nóbrega, Viviane G.& Silva, Maria Carolina S. M. da& Gomes, Hemerson Dyego de N.…[et al.]. 2019. Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients. BioMed Research International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127444
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Silva, Juliana…[et al.]. Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients. BioMed Research International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1127444
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Silva, Juliana& Brito, Beatriz S.& Silva, Isaac Neri de N.& Nóbrega, Viviane G.& Silva, Maria Carolina S. M. da& Gomes, Hemerson Dyego de N.…[et al.]. Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1127444
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127444
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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