![](/images/graphics-bg.png)
The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Zhou, Zonglei
Zhou, Ruzhen
Li, Kunpeng
Wei, Wen
Zhang, Zengqiao
Zhu, Yan
Luan, Rongsheng
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Several studies have investigated the association between Toxoplasma gondii (T.
gondii) infection and risk of Parkinson’s disease (PD) with inconsistent results.
Clarifying this relation might be useful for better understanding of the risk factors and the relevant mechanisms of PD, thus a meta-analysis was conducted to explore whether exposure to T.
gondii is associated with an increased risk of PD.
Methods.
We conducted this meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement.
A rigorous literature selection was performed by using the databases of PubMed, Embase, Web of Science, Cochrane Library, and ScienceDirect.
Odds ratio (OR) and corresponding 95% confidential interval (CI) were pooled by using fixed-effects models.
Sensitivity analysis, publication bias test, and methodological quality assessment of studies were also performed.
Results.
Seven studies involving 1086 subjects were included in this meta-analysis.
Pooled data by using fixed-effects models suggested both latent infection (OR, 1.17; 95% CI, 0.86 to 1.58; P=0.314) and acute infection (OR, 1.13; 95% CI, 0.30 to 4.35; P=0.855) were not associated with PD risk.
Stable and robust estimates were confirmed by sensitivity analysis.
No publication bias was found by visual inspection of the funnel plot, Begg’s, and Egger’s test.
Conclusions.
This meta-analysis does not support any possible association between T.
gondii infection and risk of PD.
Researches are still warranted to further explore the underlying mechanisms of T.
gondii in the pathogenesis of PD and their causal relationship.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Zonglei& Zhou, Ruzhen& Li, Kunpeng& Wei, Wen& Zhang, Zengqiao& Zhu, Yan…[et al.]. 2019. The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1127772
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Zonglei…[et al.]. The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis. BioMed Research International No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1127772
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Zonglei& Zhou, Ruzhen& Li, Kunpeng& Wei, Wen& Zhang, Zengqiao& Zhu, Yan…[et al.]. The Association between Toxoplasma gondii Infection and Risk of Parkinson’s Disease: A Systematic Review and Meta-Analysis. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1127772
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127772
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)