Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions
المؤلفون المشاركون
Wattanathorn, Jintanaporn
Prabsattroo, Thawatchai
Somsapt, Pichet
Sritragool, Opass
Muchimapura, Supaporn
Thukham-mee, Wipawee
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-25
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
In this study, we aimed to assess the effect and possible underlying mechanism of Anacardium occidentale leaves extract on male sexual behaviors in stress-exposed rats.
Male Wistar rats were orally given A.
occidentale extract at doses of 25, 100, and 200 mg/kg BW before 12-hour-immobilization exposure for 14 days.
Sexual behaviors, serum testosterone and corticosterone levels, TH-positive cells density in nucleus accumbens (NAc) and ventral tegmental area (VTA), MAO-B activity in NAc and medial preoptic area (MPOA), testis histology together with phosphodiesterase type-5 ( PDE-5) activity, and endothelial nitric oxide synthase (eNOS) expression in penis were evaluated after treatment.
All doses of extract improved male sexual behaviors, suppressed MAO-B in NAc, enhanced TH-positive cells density in NAc, suppressed PDE-5 in penis, and enhanced interstitial cell of Leydig.
The increase of serum testosterone, TH-positive cells density in VTA, eNOS expression in penis, and the decreased serum corticosterone were observed at some doses.
Therefore, the sexual enhancing effect of extract occurred mainly via the improved dopaminergic and testicular functions.
PDE-5 suppression in penis also played the role especially in the increased intromission behavior.
Therefore, A.
occidentale leaves extract is the potential protective agent against sexual dysfunction.
However, further researches are necessary.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wattanathorn, Jintanaporn& Prabsattroo, Thawatchai& Somsapt, Pichet& Sritragool, Opass& Thukham-mee, Wipawee& Muchimapura, Supaporn. 2018. Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions. BioMed Research International،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1127937
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wattanathorn, Jintanaporn…[et al.]. Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions. BioMed Research International No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1127937
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wattanathorn, Jintanaporn& Prabsattroo, Thawatchai& Somsapt, Pichet& Sritragool, Opass& Thukham-mee, Wipawee& Muchimapura, Supaporn. Sexual Enhancing Effect of Anacardium occidentale in Stress-Exposed Rats by Improving Dopaminergic and Testicular Functions. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1127937
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1127937
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر