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The Application of Nanotechnology in the Codelivery of Active Constituents of Plants and Chemotherapeutics for Overcoming Physiological Barriers during Antitumor Treatment
المؤلفون المشاركون
Yan, Zhiqiang
Li, Qiushuang
Xiong, Yang
Ji, Conghua
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-13
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
Antitumor therapy using a combination of drugs has shown increased clinical efficacy.
Active constituents derived from plants can offer several advantages, such as high efficiacy, low toxicity, extensive effects, and multiple targets.
At present, the combination of plants’ active constituents and chemotherapeutic drugs has attracted increased attention.
Nanodrug delivery systems (NDDSs) have been widely used in tumor-targeted therapy because of their efficacy of delivering antitumor drugs.
The in vivo process of tumor-targeted NDDSs has several steps.
They include blood circulation, tumor accumulation and penetration, target cell internalization and uptake, and drug release and drug response.
In each step, NDDSs encounter multiple barriers that prevent their effective delivery to target sites.
Studies have been performed to find alternative strategies to overcome these barriers.
We reviewed the recent progress of codelivery of active constituents of plants and chemotherapeutics using NDDSs.
Progress into transversing the physiological barriers for more effective in vivo antitumor delivery will be discussed in this review.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Qiushuang& Xiong, Yang& Ji, Conghua& Yan, Zhiqiang. 2019. The Application of Nanotechnology in the Codelivery of Active Constituents of Plants and Chemotherapeutics for Overcoming Physiological Barriers during Antitumor Treatment. BioMed Research International،Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1128304
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Qiushuang…[et al.]. The Application of Nanotechnology in the Codelivery of Active Constituents of Plants and Chemotherapeutics for Overcoming Physiological Barriers during Antitumor Treatment. BioMed Research International No. 2019 (2019), pp.1-16.
https://search.emarefa.net/detail/BIM-1128304
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Qiushuang& Xiong, Yang& Ji, Conghua& Yan, Zhiqiang. The Application of Nanotechnology in the Codelivery of Active Constituents of Plants and Chemotherapeutics for Overcoming Physiological Barriers during Antitumor Treatment. BioMed Research International. 2019. Vol. 2019, no. 2019, pp.1-16.
https://search.emarefa.net/detail/BIM-1128304
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128304
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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