Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Jiang, Hongchi
Yu, QingAn
Liu, KunPeng
Ma, DaKun
Wu, YaoHua
Dai, WenJie
Lv, XiaoYing
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-10
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Associations have been demonstrated between fertility drugs and a variety of hormone-sensitive carcinomas.
The purpose of this study was to determine the relationship between fertility drugs used in the treatment of female infertility and the risk of thyroid cancer.
To investigate the clinical significance of fertility drugs used for the treatment of female infertility and the risk associated with thyroid cancer, we performed a literature search using PubMed, MEDLINE, the Cochrane Library, the Web of Science, and EBSCOHOST for comparative studies published any time prior to July 21, 2017.
The studies included women who were treated for infertility with fertility drugs, such as clomiphene citrate, gonadotropins, or other unspecified fertility agents, which reported the incidence of thyroid cancer as the main outcome.
Eight studies were included in the meta-analyses.
Among women with infertility, there was a significant positive association between thyroid cancer risk and the use of fertility drugs (relative risk [RR] = 1.35; 95% confidence interval [CI] 1.12–1.64; P=0.002).
Additionally, among women with infertility, the use of clomiphene citrate was associated with an increased risk of thyroid cancer compared to women who did not use fertility drugs (RR = 1.45; 95% CI 1.12–1.88; P=0.005).
After pooling results, we found that the parity status of infertile women using fertility drugs was not associated with thyroid cancer risk (RR = 0.99; 95% CI 0.61–1.58, P=0.95).
In summary, clomiphene citrate (the most commonly used fertility drug) and other fertility drugs are associated with an increased risk of thyroid cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yu, QingAn& Lv, XiaoYing& Liu, KunPeng& Ma, DaKun& Wu, YaoHua& Dai, WenJie…[et al.]. 2018. Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1128318
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yu, QingAn…[et al.]. Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis. BioMed Research International No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1128318
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yu, QingAn& Lv, XiaoYing& Liu, KunPeng& Ma, DaKun& Wu, YaoHua& Dai, WenJie…[et al.]. Fertility Drugs Associated with Thyroid Cancer Risk: A Systematic Review and Meta-Analysis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1128318
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128318
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر