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Spermatogenesis Abnormalities following Hormonal Therapy in Transwomen
المؤلفون المشاركون
Selvaggi, Gennaro
Jindarak, Sirachai
Angspatt, Apichai
Pungrasmi, Pornthep
Suwajo, Poonpismai
Tiewtranon, Preecha
Nilprapha, Kasama
Atikankul, Taywin
Iamphongsai, Seree
Promniyom, Pasu
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-02
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To measure spermatogenesis abnormalities in transwomen at the time of sex reassignment surgery (SRS) and to analyze the association between hormonal therapy duration and infertility severity.
Design.
Retrospective study.
Setting.
University hospital.
Patients.
One-hundred seventy-three transwomen who underwent SRS from January 2000 to December 2015.
Interventions.
All orchidectomy specimens were retrospectively reviewed and classified.
History of hormonal therapy duration was retrieved from medical records.
Main Outcome Measures.
Histological examinations of orchidectomy specimens were performed to assess spermatogenesis.
Results.
One-hundred seventy-three orchidectomy specimens were evaluated.
Histological examinations showed maturation arrest in 36.4%, hypospermatogenesis in 26%, Sertoli cell-only syndrome in 20.2%, normal spermatogenesis in 11%, and seminiferous tubule hyalinization in 6.4% of the specimens.
Spermatogenesis abnormality severity was not associated with the total therapy duration (P=0.81) or patient age at the time of surgery (P=0.88).
Testicular volumes and sizes were associated with spermatogenesis abnormality severity (P=0.001 and P=0.026, right testicle and left testicle, resp.).
Conclusion(s).
Feminizing hormonal treatment leads to reductions in testicular germ cell levels.
All transwomen should be warned about this consequence, and gamete preservation should be offered before starting hormonal treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jindarak, Sirachai& Nilprapha, Kasama& Atikankul, Taywin& Angspatt, Apichai& Pungrasmi, Pornthep& Iamphongsai, Seree…[et al.]. 2018. Spermatogenesis Abnormalities following Hormonal Therapy in Transwomen. BioMed Research International،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1128785
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jindarak, Sirachai…[et al.]. Spermatogenesis Abnormalities following Hormonal Therapy in Transwomen. BioMed Research International No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1128785
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jindarak, Sirachai& Nilprapha, Kasama& Atikankul, Taywin& Angspatt, Apichai& Pungrasmi, Pornthep& Iamphongsai, Seree…[et al.]. Spermatogenesis Abnormalities following Hormonal Therapy in Transwomen. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1128785
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128785
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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