The Effect of Vitamin E and Metallothionein on the Antioxidant Capacities of Cadmium-Damaged Liver in Grass Carp Ctenopharyngodon idellus
المؤلفون المشاركون
Ou, Yangping
Geng, Yi
Feng, Yang
Huang, Xiaoli
Duan, Yajiao
Fan, Wei
Duan, Jing
Wang, Kaiyu
Deng, Yongqiang
Chen, Defang
Yang, Shiyong
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Cadmium (Cd) causes a broad spectrum of toxicological effects to animals.
Aquatic animals were more likely to accumulate Cd than terrestrial animals because of the living environment.
Clearance of Cd in aquatic animals has become an important part of aquatic food safety.
The present study was focused on the oxidative damage induced by Cd in the liver of grass carp Ctenopharyngodon idellus and the protective effect of vitamin E (VE) and metallothionein (MT).
Grass carp were divided into four groups: the control group, Cd+phosphate-buffered saline (PBS) group, Cd+VE group, and Cd+MT group.
All fish were injected with CdCl2 on the first day and then VE, MT, and PBS were given 4 days after injection, respectively.
The liver function and antioxidant capacity of grass carp were evaluated.
Cd administration resulted in damage of liver function and morphology in liver, which was expressed as the increased content of AST and ALT, rupture of organelles, and decrease of CAT, SOD, and GSH-Px activity.
However, VE and MT treatments protected against Cd-induced damage of liver in grass carp by decreasing AST and ALT content, repairing organelles, and maintained the antioxidant system by elevating CAT, SOD, and GSH-Px activity and regulating related mRNA transcript expression.
The results revealed that VE and MT might play an important role in the treatment of heavy metal poisoning through their antioxidative effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Feng, Yang& Huang, Xiaoli& Duan, Yajiao& Fan, Wei& Duan, Jing& Wang, Kaiyu…[et al.]. 2018. The Effect of Vitamin E and Metallothionein on the Antioxidant Capacities of Cadmium-Damaged Liver in Grass Carp Ctenopharyngodon idellus. BioMed Research International،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128795
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Feng, Yang…[et al.]. The Effect of Vitamin E and Metallothionein on the Antioxidant Capacities of Cadmium-Damaged Liver in Grass Carp Ctenopharyngodon idellus. BioMed Research International No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1128795
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Feng, Yang& Huang, Xiaoli& Duan, Yajiao& Fan, Wei& Duan, Jing& Wang, Kaiyu…[et al.]. The Effect of Vitamin E and Metallothionein on the Antioxidant Capacities of Cadmium-Damaged Liver in Grass Carp Ctenopharyngodon idellus. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1128795
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128795
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر