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A Comparison of the Immunostimulatory Effects of Polysaccharides from Tetraploid and Diploid Echinacea purpurea
المؤلفون المشاركون
Yang, Guang
Li, Keke
Liu, Cui
Peng, Peipei
Bai, Mei
Sun, Jiaqi
Li, Qingling
Yang, Zhuohong
Yang, Yue-Sheng
Wu, Hong
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-09
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Polyploidization is an effective means of improving the active components and quality of secondary metabolism in medicinal plants.
In the present study, we compared the immunostimulatory effects of crude polysaccharides from tetraploid and diploid Echinacea purpurea.
The results showed that the carbohydrate contents of crude polysaccharide of tetraploid E.
purpurea (CPE4) and diploid E.
purpurea (CPE2) were 85.51% and 44.65%, respectively.
1H-nuclear magnetic resonance (NMR) spectroscopy and gel-permeation chromatography (GPC) analyses showed no major differences in the overall structure and molecular weight of polysaccharides between CPE4 and CPE2.
However, some differences in the relative content of the same polysaccharides group were observed between CPE4 and CPE2.
In in vitro tests, EP4 could stimulate lymphocyte proliferation and secretion of cytokines maximally at the concentration of 0.0312 mg/mL, and EP2 could stimulate lymphocyte proliferation and secretion of cytokines maximally at the concentration of 0.125 mg/mL.
In in vivo tests, EP4 was more effective at promoting the proliferation of lymphocytes and secretion of cytokines in mice immunosuppressed by cyclophosphamide than EP2 at the same concentration.
Taken together, these data demonstrated that the relative content of the partial polysaccharides group is increased, and the immunoregulatory effect is enhanced in tetraploid E.
purpurea.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Guang& Li, Keke& Liu, Cui& Peng, Peipei& Bai, Mei& Sun, Jiaqi…[et al.]. 2018. A Comparison of the Immunostimulatory Effects of Polysaccharides from Tetraploid and Diploid Echinacea purpurea. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1129255
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Guang…[et al.]. A Comparison of the Immunostimulatory Effects of Polysaccharides from Tetraploid and Diploid Echinacea purpurea. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1129255
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Guang& Li, Keke& Liu, Cui& Peng, Peipei& Bai, Mei& Sun, Jiaqi…[et al.]. A Comparison of the Immunostimulatory Effects of Polysaccharides from Tetraploid and Diploid Echinacea purpurea. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1129255
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129255
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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