Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis
المؤلفون المشاركون
Ephraim, Richard K. D.
Sakyi, Samuel A.
Owiredu, William K. B. A.
Laing, Edwin F.
Owiredu, Eddie-Williams
Fondjo, Linda Ahenkorah
Awusi, Ebenezer Kwesi
Kantanka, Osei Sarfo
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-02
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Type 2 Diabetes Mellitus (T2DM) and menopause are associated with vitamin D status.
Oestrogen decline during menopausal stages promotes hypovitaminosis D.
However, the interplay between vitamin D, menopause, lifestyle, and T2DM cannot be overlooked.
This study assessed vitamin D status among pre- and postmenopausal T2DM women and determined its association with glycemic control and influence of lifestyle habits on hypovitaminosis D.
Methods.
This cross-sectional study was conducted at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Structured questionnaires were administered to 192 T2DM women; blood samples were collected for estimation of 25(OH) D and insulin using ELISA.
Fasting blood glucose (FBG), lipid profile, glycated haemoglobin (HbA1c), and calcium were measured.
Statistical analyses were performed using Graphpad Prism 6.
Results.
The prevalence of vitamin D inadequacy was 92.2%.
Hypovitaminosis D was more prevalent among the postmenopausal T2DM women (63.8% versus 58.2%).
Hypovitaminosis D significantly associated with insulin [R2=0.01760, p=0.0008], HbA1c [R2=0.3709, p=<0.0001], and FBG [R2=0.3465, p=0.0001] in only the postmenopausal women.
Conclusion.
Vitamin D deficiency is prevalent in pre- and postmenopausal T2DM but higher among postmenopausal women.
Adequate vitamin D levels in both groups were associated with improved glucose control while hypovitaminosis D in the postmenopausal women was related to poorer glucose control.
Vitamin D screening should be incorporated into management plan for T2DM to serve as an early tool for prevention of vitamin D deficiency.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fondjo, Linda Ahenkorah& Sakyi, Samuel A.& Owiredu, William K. B. A.& Laing, Edwin F.& Owiredu, Eddie-Williams& Awusi, Ebenezer Kwesi…[et al.]. 2018. Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis. BioMed Research International،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1129702
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fondjo, Linda Ahenkorah…[et al.]. Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis. BioMed Research International No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1129702
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fondjo, Linda Ahenkorah& Sakyi, Samuel A.& Owiredu, William K. B. A.& Laing, Edwin F.& Owiredu, Eddie-Williams& Awusi, Ebenezer Kwesi…[et al.]. Evaluating Vitamin D Status in Pre- and Postmenopausal Type 2 Diabetics and Its Association with Glucose Homeostasis. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1129702
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129702
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر