The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study
المؤلفون المشاركون
Kitae, Aya
Hashimoto, Yoshitaka
Hamaguchi, Masahide
Obora, Akihiro
Kojima, Takao
Fukui, Michiaki
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The triglyceride and glucose index (TyG), defined as the product of triglycerides (TG) and fasting plasma glucose (FPG), is reported as a surrogate index for insulin resistance.
Although a cross-sectional study revealed the association between the TyG-index and the prevalence of nonalcoholic fatty liver disease (NAFLD), few studies have investigated the association between the TyG-index and incident NAFLD.
Here we investigated whether the TyG-index can be used to predict incident NAFLD.
Methods.
This historical cohort study included 16,093 apparently healthy Japanese individuals.
The TyG-index was calculated by the established formula: TyG = Ln [TG (mg/dl) × FPG (mg/dl)/2].
Fatty liver was diagnosed based on the subjects’ abdominal ultrasonography results.
We divided the subjects into tertiles according to the levels of TyG-index.
Hazard ratios (HRs) of the TyG-index for incident NAFLD were calculated by a Cox proportional hazards regression model.
Results.
During the observation period, 27.4% of the men and 11.0% of the women developed NAFLD.
The highest TyG-index tertile (men, 8.48 ≤ TyG and women, 7.97 ≤ TyG) (adjusted HR 1.67, 95% CI 1.44–1.94, p<0.001 in the men and 2.06, 1.59–2.70, p<0.001 in the women) and the middle TyG-index tertile (men, 8.00 < TyG ≤ 8.48 and women, 7.53 Conclusions. Our findings demonstrate that the TyG-index is significantly associated with incident NAFLD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kitae, Aya& Hashimoto, Yoshitaka& Hamaguchi, Masahide& Obora, Akihiro& Kojima, Takao& Fukui, Michiaki. 2019. The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. Canadian Journal of Gastroenterology and Hepatology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1129851
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kitae, Aya…[et al.]. The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. Canadian Journal of Gastroenterology and Hepatology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1129851
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kitae, Aya& Hashimoto, Yoshitaka& Hamaguchi, Masahide& Obora, Akihiro& Kojima, Takao& Fukui, Michiaki. The Triglyceride and Glucose Index Is a Predictor of Incident Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study. Canadian Journal of Gastroenterology and Hepatology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1129851
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129851
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر