Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease
المؤلفون المشاركون
Ou, Hongjie
Fu, Yaojie
Liao, Wei
Zheng, Caixia
Wu, Xiaolu
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
We aimed at analyzing the role of smoking in hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD) and at exploring the related risk factors.
Methods.
This was a cross-sectional study that included a total of 225 patients with NAFLD.
Among them, 127 were nonsmokers and 98 were smokers.
Liver significant fibrosis was diagnosed when the liver stiffness (LS) value was higher than 7.4 kPa.
The diagnostic criterion for NAFLD was a controlled attenuation parameter (CAP) value of >238 dB/m.
The CAP and LS values were measured using FibroScan.
Results.
FibroScan showed that the LS value in the smokers was significantly higher than that in the nonsmokers (10.12 ± 10.38 kPa vs.
7.26 ± 6.42 kPa, P=0.013).
The proportions of patients with liver significant fibrosis and advanced liver fibrosis among the smokers were significantly higher than those among the nonsmokers (P=0.046).
Univariate analysis showed that age, weight, high AST level, low PLT level, and smoking were the risk factors associated with liver fibrosis in the smokers with NAFLD while multivariate analysis showed that age (OR = 1.029, P=0.021), high AST level (OR = 1.0121, P=0.025), and smoking (OR = 1.294, P=0.015) were the independent risk factors associated with liver fibrosis in the patients with NAFLD.
Moreover, high AST level (OR = 1.040, P=0.029), smoking index (OR = 1.220, P=0.019), and diabetes mellitus (OR = 1.054, P=0.032) were the independent risk factors for liver fibrosis among the smokers with NAFLD.
Conclusion.
This study showed that smoking was closely associated with liver fibrosis among the patients with NAFLD.
For patients with NAFLD who smoke, priority screening and timely intervention should be provided if they are at risk of liver fibrosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ou, Hongjie& Fu, Yaojie& Liao, Wei& Zheng, Caixia& Wu, Xiaolu. 2019. Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease. Canadian Journal of Gastroenterology and Hepatology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1129883
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ou, Hongjie…[et al.]. Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease. Canadian Journal of Gastroenterology and Hepatology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1129883
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ou, Hongjie& Fu, Yaojie& Liao, Wei& Zheng, Caixia& Wu, Xiaolu. Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease. Canadian Journal of Gastroenterology and Hepatology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1129883
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129883
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر