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Weight Loss in Parkinson’s Disease: The Relationship with Motor Symptoms and Disease Progression
المؤلفون المشاركون
Cersosimo, Maria Graciela
Raina, Gabriela B.
Pellene, Luis A.
Micheli, Federico E.
Calandra, Cristian R.
Maiola, Ricardo
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
To determine the prevalence of weight loss (WL) in PD patients, its relationship to the severity of motor manifestations and appetite changes.
Methods.
144 PD patients and 120 controls were evaluated in a single session.
All subjects were asked about changes in body weight and appetite.
PD patients were examined with the UPDRS-III and the Hoehn and Yahr (HY) scales.
Subscores of tremor, bradykinesia /rigidity, and non-dopaminergic symptoms (NDS) were analyzed individually.
Multivariable logistic regression analysis was used to determine an association between WL and PD motor manifestations.
Results.
48.6 % of PD patients presented WL compared to 20.8 % of controls (p < 0.001).
Weight losers were significantly older and had longer disease duration, higher scores in HY stages, UPDRS-III, and NDS-subscore.
Multivariable logistic regression analysis demonstrated that WL was associated with NDS-subscore (p= 0.002; OR: 1.33) and older age (p= 0.037; OR: 1.05).
Appetite in PD cases losing weight was unchanged (35.7 %), decreased (31.4 %), or even increased (32.9).
Conclusions.
Our results showed that WL occurs in almost half of PD patients and it is largely the consequence of disease progression rather than involuntary movements or a decrease in food intake.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cersosimo, Maria Graciela& Raina, Gabriela B.& Pellene, Luis A.& Micheli, Federico E.& Calandra, Cristian R.& Maiola, Ricardo. 2018. Weight Loss in Parkinson’s Disease: The Relationship with Motor Symptoms and Disease Progression. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1129938
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cersosimo, Maria Graciela…[et al.]. Weight Loss in Parkinson’s Disease: The Relationship with Motor Symptoms and Disease Progression. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1129938
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cersosimo, Maria Graciela& Raina, Gabriela B.& Pellene, Luis A.& Micheli, Federico E.& Calandra, Cristian R.& Maiola, Ricardo. Weight Loss in Parkinson’s Disease: The Relationship with Motor Symptoms and Disease Progression. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1129938
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1129938
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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