Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer

المؤلفون المشاركون

Qian, Hui
Xu, Wenrong
Yan, Yongmin
Zhang, Xu
Mao, Fei
Kang, Jingjing
Zhang, Li
Luo, Xiao
Ma, Xiangyu
Wang, Gaoying
Yang, Yanhui

المصدر

BioMed Research International

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-16، 16ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-12-26

دولة النشر

مصر

عدد الصفحات

16

التخصصات الرئيسية

الطب البشري

الملخص EN

Mesenchymal stem cells (MSCs) therapy has been applied to a wide range of diseases with excessive immune response, including inflammatory bowel disease (IBD), owing to its powerful immunosuppression and its ability to repair tissue lesions.

Different sources of MSCs show different therapeutic properties.

Engineering managements are able to enhance the immunomodulation function and the survival of MSCs involved in IBD.

The therapeutic mechanism of MSCs in IBD mainly focuses on cell-to-cell contact and paracrine actions.

One of the promising therapeutic options for IBD can focus on exosomes of MSCs.

MSCs hold promise for the treatment of IBD-associated colorectal cancer because of their tumor-homing function and chronic inflammation inhibition.

Encouraging results have been obtained from clinical trials in IBD and potential challenges caused by MSCs therapy are getting solved.

This review can assist investigators better to understand the research progress for enhancing the efficacy of MSCs therapy involved in IBD and CAC.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kang, Jingjing& Zhang, Li& Luo, Xiao& Ma, Xiangyu& Wang, Gaoying& Yang, Yanhui…[et al.]. 2018. Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer. BioMed Research International،Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1129955

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kang, Jingjing…[et al.]. Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer. BioMed Research International No. 2018 (2018), pp.1-16.
https://search.emarefa.net/detail/BIM-1129955

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kang, Jingjing& Zhang, Li& Luo, Xiao& Ma, Xiangyu& Wang, Gaoying& Yang, Yanhui…[et al.]. Systematic Exposition of Mesenchymal Stem Cell for Inflammatory Bowel Disease and Its Associated Colorectal Cancer. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-16.
https://search.emarefa.net/detail/BIM-1129955

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1129955