Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe
المؤلفون المشاركون
Boldogkői, Zsolt
Csabai, Zsolt
Tombácz, Dóra
Deim, Zoltán
Snyder, Michael
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-04
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Pseudorabies virus (PRV) is the causative agent of Aujeszky’s disease giving rise to significant economic losses worldwide.
Many countries have implemented national programs for the eradication of this virus.
In this study, long-read sequencing was used to determine the nucleotide sequence of the genome of a novel PRV strain (PRV-MdBio) isolated in Serbia.
Results.
In this study, a novel PRV strain was isolated and characterized.
PRV-MdBio was found to exhibit similar growth properties to those of another wild-type PRV, the strain Kaplan.
Single-molecule real-time (SMRT) sequencing has revealed that the new strain differs significantly in base composition even from strain Kaplan, to which it otherwise exhibits the highest similarity.
We compared the genetic composition of PRV-MdBio to strain Kaplan and the China reference strain Ea and obtained that radical base replacements were the most common point mutations preceding conservative and silent mutations.
We also found that the adaptation of PRV to cell culture does not lead to any tendentious genetic alteration in the viral genome.
Conclusion.
PRV-MdBio is a wild-type virus, which differs in base composition from other PRV strains to a relatively large extent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Csabai, Zsolt& Tombácz, Dóra& Deim, Zoltán& Snyder, Michael& Boldogkői, Zsolt. 2019. Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1130010
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Csabai, Zsolt…[et al.]. Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1130010
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Csabai, Zsolt& Tombácz, Dóra& Deim, Zoltán& Snyder, Michael& Boldogkői, Zsolt. Analysis of the Complete Genome Sequence of a Novel, Pseudorabies Virus Strain Isolated in Southeast Europe. Canadian Journal of Infectious Diseases and Medical Microbiology. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1130010
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130010
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر