In Vitro Antibacterial Interaction of Doripenem and Amikacin against Multidrug-Resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae Isolates
المؤلفون المشاركون
Loho, Tonny
Sukartini, Ninik
Astrawinata, Dalima A. W.
Immanuel, Suzanna
Aulia, Diana
Priatni, Ika
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Evaluation of the in vitro interaction of doripenem and amikacin against Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae was done by classifying them into four groups: doripenem and amikacin sensitive (DOR-S/AMK-S), doripenem sensitive and amikacin resistant (DOR-S/AMK-R), doripenem resistant and amikacin sensitive (DOR-R/AMK-S), and both doripenem and amikacin resistant (DOR-R/AMK-R).
The MIC of each antibiotic and their combination was obtained using the Etest method.
The fractional inhibitory concentration index was calculated to classify the results as synergistic, additive, indifferent, or antagonistic interaction.
In the DOR-S/AMK-S class, 1 isolate of A.
baumannii showed synergy and the other 5 showed additive results, 5 isolates of P.
aeruginosa showed additive and 1 isolate showed indifferent result, and 2 isolates of K.
pneumoniae showed additive and the other 4 showed indifferent results.
In the DOR-S/AMK-R class, 3 isolates of A.
baumannii showed additive and the other 3 showed indifferent results, 2 isolates of P.
aeruginosa showed indifferent results, and 1 isolate of K.
pneumoniae showed additive and the other 5 showed indifferent results.
In the DOR-R/AMK-S class, 1 isolate of A.
baumannii showed additive and the other 5 showed indifferent results, 1 isolate of P.
aeruginosa showed additive and the other 5 showed indifferent results, and 4 isolates of K.
pneumoniae showed additive and the other 2 showed indifferent results.
In the DOR-R/AMK-R class, 6 isolates of A.
baumannii showed indifferent results, 1 isolate of P.
aeruginosa showed additive and the other 5 showed indifferent results, and 1 isolate of K.
pneumoniae showed additive and the other 5 showed indifferent results.
Synergy occurred in only 1 (1.5%) isolate.
Additive interaction occurred in 24 (35.3%) isolates, and indifferent interaction occurred in 43 (63.2%) isolates.
Doripenem sensitive combined with amikacin sensitive reduced MIC significantly in all bacterial isolates when compared to single MIC of each antibiotic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Loho, Tonny& Sukartini, Ninik& Astrawinata, Dalima A. W.& Immanuel, Suzanna& Aulia, Diana& Priatni, Ika. 2018. In Vitro Antibacterial Interaction of Doripenem and Amikacin against Multidrug-Resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae Isolates. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131117
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Loho, Tonny…[et al.]. In Vitro Antibacterial Interaction of Doripenem and Amikacin against Multidrug-Resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae Isolates. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1131117
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Loho, Tonny& Sukartini, Ninik& Astrawinata, Dalima A. W.& Immanuel, Suzanna& Aulia, Diana& Priatni, Ika. In Vitro Antibacterial Interaction of Doripenem and Amikacin against Multidrug-Resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae Isolates. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131117
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131117
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر