Prevalence and Risk Factors of Active TB among Adult HIV Patients Receiving ART in Northwestern Tanzania: A Retrospective Cohort Study
المؤلفون المشاركون
Shao, Elichilia
Mpondo, Bonaventura C. T.
Kalluvya, Samuel
Gunda, Daniel W.
Kilonzo, Semvua B.
Maganga, Simon C.
Nkandala, Igembe
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Although ART has improved the outcome of people living with HIV/AIDS, still some patients develop TB while receiving ART.
The literature on the magnitude of this problem is still scarce in our setting especially northwestern Tanzania.
This study was designed to determine the prevalence of active TB among HIV patients on ART and assess its potential risk factors.
Methods.
A retrospective cohort study was done among adult HIV-positive patients initiated on ART at Bugando Medical Centre.
Patients who were TB positive before ART initiation were excluded.
Data regarding demographic, clinical, and laboratory information, TB status on receipt of ART, and time on ART were collected and analyzed using STATA 11 to determine the prevalence of TB and its associated factors.
Results.
In total, 391 patients were enrolled in this study.
The median age was 39 (32–46) years, and a total of 129 (32.99%) participants had CD4 counts <200 cells/µl and 179 (45.78%) had WHO stage 3 and 4 illnesses.
A total of 43 (11.0%) participants developed TB while receiving ART which was independently associated with male gender (OR = 2.9; p=0.007), WHO clinical stage 3 and 4 (OR = 1.4; p=0.029), baseline CD4 count <200 cells/µl (OR = 9.1; p<0.001), and having not used IPT (OR = 3.1; p=0.05).
Conclusions.
Active TB is prevalent among HIV patients while receiving ART in northwestern Tanzania which is independently associated with male gender, advanced HIV disease, and nonuse of IPT.
Universal HIV testing could reduce late HIV diagnosis and hence reduce the risk of developing TB while receiving ART in our setting.
Also IPT should be widely used for those who are negative for TB on screening.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gunda, Daniel W.& Maganga, Simon C.& Nkandala, Igembe& Kilonzo, Semvua B.& Mpondo, Bonaventura C. T.& Shao, Elichilia…[et al.]. 2018. Prevalence and Risk Factors of Active TB among Adult HIV Patients Receiving ART in Northwestern Tanzania: A Retrospective Cohort Study. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131119
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gunda, Daniel W.…[et al.]. Prevalence and Risk Factors of Active TB among Adult HIV Patients Receiving ART in Northwestern Tanzania: A Retrospective Cohort Study. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1131119
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gunda, Daniel W.& Maganga, Simon C.& Nkandala, Igembe& Kilonzo, Semvua B.& Mpondo, Bonaventura C. T.& Shao, Elichilia…[et al.]. Prevalence and Risk Factors of Active TB among Adult HIV Patients Receiving ART in Northwestern Tanzania: A Retrospective Cohort Study. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131119
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131119
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر