Prognostic Value of Volume-Based Positron Emission TomographyComputed Tomography in Nasopharyngeal Carcinoma Patients after Comprehensive Therapy
المؤلفون المشاركون
Zhang, Yongxue
Lan, Xiaoli
Tian, Yueli
Bakari, Khamis Hassan
Liao, Shanshan
Xia, Xiaotian
Sun, Xun
Qin, Chunxia
المصدر
Contrast Media & Molecular Imaging
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
We assessed the prognostic value of standardized uptake value (SUV) and volume-based methods including whole-body metabolic tumor volume (WBMTV) and whole-body total lesion glycolysis (WBTLG) using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) of patients with nasopharyngeal carcinoma (NPC) after therapy.
Methods.
A total of 221 posttherapy NPC cases were enrolled, all of whom had undergone PET/CT scanning and follow-up in this retrospective study.
The diagnostic results of PET/CT were analyzed and compared with histopathological diagnosis or clinical follow-up.
Receiver operator characteristic curves, the Kaplan-Meier method, and the log-rank test were used to assess the optimal cutoff values for WBMTV and WBTLG to identify independent predictors of survival.
Results.
The detection rates of the threshold SUV were 2.5, 20%, and 40%, and SUV background methods were 65.6% (378/576), 80.2% (462/576), 71.5% (412/576), and 90.4% (521/576), respectively (P<0.005).
Patients with a WBMTV < 8.10 and/or a WBTLG < 35.58 had significantly better 5-year overall survival than those above the cutoffs (90.7% versus 51.2%, P<0.001; 91.7% versus 50.4%, P<0.001), respectively.
Multivariate Cox regression modeling showed both WBTLG (RR, 1.002; P=0.004) and age (RR, 1.046; P=0.006) could be used to predict overall survival.
WBTLG (RR, 1.003; P<0.001) may have predictive relevance in estimating disease-free survival.
Conclusions.
SUV volume-based threshold background methodology had a significantly higher detection rate for metastatic lesions.
WBTLG could be used as an independent prognostic indicator for posttherapy NPC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tian, Yueli& Bakari, Khamis Hassan& Liao, Shanshan& Xia, Xiaotian& Sun, Xun& Qin, Chunxia…[et al.]. 2018. Prognostic Value of Volume-Based Positron Emission TomographyComputed Tomography in Nasopharyngeal Carcinoma Patients after Comprehensive Therapy. Contrast Media & Molecular Imaging،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131291
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tian, Yueli…[et al.]. Prognostic Value of Volume-Based Positron Emission TomographyComputed Tomography in Nasopharyngeal Carcinoma Patients after Comprehensive Therapy. Contrast Media & Molecular Imaging No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1131291
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tian, Yueli& Bakari, Khamis Hassan& Liao, Shanshan& Xia, Xiaotian& Sun, Xun& Qin, Chunxia…[et al.]. Prognostic Value of Volume-Based Positron Emission TomographyComputed Tomography in Nasopharyngeal Carcinoma Patients after Comprehensive Therapy. Contrast Media & Molecular Imaging. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131291
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1131291
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر