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Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement
المؤلفون المشاركون
Pedersen, Michael
Madsen, Jesper Guldsmed
Andersen, Henning
Østergaard, Jakob Appel
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aims/Hypothesis.
The complications affecting the peripheral nervous system, associated with diabetes mellitus, have been the focus of considerable research.
Comparably less research has focused upon the effect of diabetes upon the central nervous system.
In this study, we investigate the effect of diabetes upon motor-neuron potentials evoked in the motor cortex of streptozotocin diabetic rats.
Methods.
In this study, we investigated the cortical-evoked motor-neuron potentials in streptozotocin-induced diabetic rats.
Cortical potentials were evoked using direct current stimulation to the motor cortex, and the resulting evoked potentials were recorded in the sciatic nerve.
As voluntary movement consists of repeated activation of muscles, repeated stimulation trials were used to determine the effect of diabetes upon the animals’ ability to recuperate between stimulations.
Results.
Our findings showed that diabetes severely decreased the amplitude of cortical-evoked potentials and compromised the recuperation of motor neurons between activation.
Conclusion/Interpretation.
The reduced amplitude and weakened recuperation of diabetic motor neurons potentially may contribute to impaired transmission in motor pathways and thereby motor dysfunction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Madsen, Jesper Guldsmed& Østergaard, Jakob Appel& Andersen, Henning& Pedersen, Michael. 2020. Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement. BioMed Research International،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1132176
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Madsen, Jesper Guldsmed…[et al.]. Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement. BioMed Research International No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1132176
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Madsen, Jesper Guldsmed& Østergaard, Jakob Appel& Andersen, Henning& Pedersen, Michael. Attenuation of Cortically Evoked Motor-Neuron Potential in Streptozotocin-Induced Diabetic Rats: A Study about the Effect of Diabetes upon Cortical-Initiated Movement. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1132176
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132176
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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