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Significance of Hepatitis B Recurrence in Liver Transplantation Recipients
المؤلفون المشاركون
Lee, Wei-Chen
Wu, Tsung-Han
Wang, Yu-Chao
Chou, Hong-Shiue
Hung, Hao-Chien
Lee, Jin-Chiao
Lee, Chen-Fang
Chan, Kun-Ming
Wu, Ting-Jung
Cheng, Chih-Hsien
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
A combination of antihepatitis B immunoglobulin and antiviral agents is the most common regimen for prophylaxis of hepatitis B recurrence after liver transplantation.
However, hepatitis B recurrence still happens.
The significance of hepatitis B recurrence is less mentioned.
Materials.
Forty-eight of the 313 hepatitis B liver transplant recipients having hepatitis B recurrence were included in this study.
The patients were divided into group A, the patients transplanted for hepatitis B-related liver failure, and group B, the patients transplanted for hepatitis B-related cirrhosis and HCC.
The clinical manifestations after hepatitis B recurrence were recorded.
Results.
Among the 48 patients with hepatitis B recurrence, 23 patients were in group A and 25 patients in group B.
The age was 51.6±9.4 years in group A and 52.8±6.4 in group B (p=0.869).
The MELD score prior to transplantation was 23.1±9.9 in group A patients and 12.9±5.6 in group B patients (p<0.001).
The median (interquartile) interval from transplantation to hepatitis B recurrence was 10 (2-19) months for group A patients and 13 (8.5-35) months for group B patients (p=0.051).
After hepatitis B recurrence, the liver function was almost normal in both groups.
In group B patients, 10 patients had HCC recurrence with 7 of 10 patients having hepatitis B recurrence earlier than HCC recurrence.
The interval between hepatitis B and HCC recurrence was 1 to 15 months.
The 1-, 3-, and 5-year survival rates were 82.6%, 73.9%, and 69.0%, respectively, for group A patients and 96%, 76%, and 68%, respectively, for group B patients (p=0.713).
Conclusion.
The patients have uneventful liver function under antiviral agent while hepatitis B recurred.
For the patients having HCC prior to transplantation, close monitoring of HCC recurrence is necessary if hepatitis B recurs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chou, Hong-Shiue& Cheng, Chih-Hsien& Hung, Hao-Chien& Lee, Jin-Chiao& Wang, Yu-Chao& Wu, Tsung-Han…[et al.]. 2020. Significance of Hepatitis B Recurrence in Liver Transplantation Recipients. BioMed Research International،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1132546
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chou, Hong-Shiue…[et al.]. Significance of Hepatitis B Recurrence in Liver Transplantation Recipients. BioMed Research International No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1132546
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chou, Hong-Shiue& Cheng, Chih-Hsien& Hung, Hao-Chien& Lee, Jin-Chiao& Wang, Yu-Chao& Wu, Tsung-Han…[et al.]. Significance of Hepatitis B Recurrence in Liver Transplantation Recipients. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1132546
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1132546
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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