High-Density Lipoprotein Cholesterol, Blood Urea Nitrogen, and Serum Creatinine Can Predict Severe Acute Pancreatitis

المؤلفون المشاركون

Zhou, Mengtao
Geng, Wujun
Hong, Wandong
Lin, Suhan
Zippi, Maddalena
Stock, Simon
Zimmer, Vincent
Xu, Chunfang

المصدر

BioMed Research International

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-08-22

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الطب البشري

الملخص EN

Background and Aims.

Early prediction of disease severity of acute pancreatitis (AP) would be helpful for triaging patients to the appropriate level of care and intervention.

The aim of the study was to develop a model able to predict Severe Acute Pancreatitis (SAP).

Methods.

A total of 647 patients with AP were enrolled.

The demographic data, hematocrit, High-Density Lipoprotein Cholesterol (HDL-C) determinant at time of admission, Blood Urea Nitrogen (BUN), and serum creatinine (Scr) determinant at time of admission and 24 hrs after hospitalization were collected and analyzed statistically.

Results.

Multivariate logistic regression indicated that HDL-C at admission and BUN and Scr at 24 hours (hrs) were independently associated with SAP.

A logistic regression function (LR model) was developed to predict SAP as follows: −2.25–0.06 HDL-C (mg/dl) at admission + 0.06 BUN (mg/dl) at 24 hours + 0.66 Scr (mg/dl) at 24 hours.

The optimism-corrected c-index for LR model was 0.832 after bootstrap validation.

The area under the receiver operating characteristic curve for LR model for the prediction of SAP was 0.84.

Conclusions.

The LR model consists of HDL-C at admission and BUN and Scr at 24 hours, representing an additional tool to stratify patients at risk of SAP.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Hong, Wandong& Lin, Suhan& Zippi, Maddalena& Geng, Wujun& Stock, Simon& Zimmer, Vincent…[et al.]. 2017. High-Density Lipoprotein Cholesterol, Blood Urea Nitrogen, and Serum Creatinine Can Predict Severe Acute Pancreatitis. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134096

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Hong, Wandong…[et al.]. High-Density Lipoprotein Cholesterol, Blood Urea Nitrogen, and Serum Creatinine Can Predict Severe Acute Pancreatitis. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1134096

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Hong, Wandong& Lin, Suhan& Zippi, Maddalena& Geng, Wujun& Stock, Simon& Zimmer, Vincent…[et al.]. High-Density Lipoprotein Cholesterol, Blood Urea Nitrogen, and Serum Creatinine Can Predict Severe Acute Pancreatitis. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134096

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1134096