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Association of Urine AlbuminCreatinine Ratio below 30 mgg and Left Ventricular Hypertrophy in Patients with Type 2 Diabetes
المؤلفون المشاركون
Lai, Wenyan
Xie, Xiangkun
Peng, Zhengliang
Li, Hanlin
Li, Dan
Tu, Yan
Bai, Yujia
Huang, Xingfu
Zhan, Qiong
Zeng, Qingchun
Xu, Dingli
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-22
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Several studies show that even a level of urine albumin/creatinine ratio (UACR) within the normal range (below 30 mg/g) increases the risk of cardiovascular diseases.
We speculate that mildly increased UACR is related to left ventricular hypertrophy (LVH) in patients with type 2 diabetes mellitus (T2DM).
In this retrospective study, 317 patients with diabetes with normal UACR, of whom 62 had LVH, were included.
The associations between UACR and laboratory indicators, as well as LVH, were examined using multivariate linear regression and logistic regression, respectively.
The diagnostic efficiency and the optimal cutoff point of UACR for LVH were evaluated using the area under the receiver operating characteristic curve (AUC) and Youden index.
Our results showed that patients with LVH had significantly higher UACR than those without LVH (P<0.001).
The prevalence of LVH presented an upward trend with the elevation of UACR.
UACR was independently and positively associated with hemoglobin A1c (P<0.001).
UACR can differentiate LVH (AUC = 0.682, 95% CI (0.602–0.760), P<0.001).
The optimal cutoff point determined with the Youden index was UACR = 10.2 mg/g.
When categorized by this cutoff point, the odds ratio (OR) for LVH in patients in the higher UACR group (10.2–30 mg/g) was 3.104 (95% CI: 1.557–6.188, P=0.001) compared with patients in the lower UACR group (<10.2 mg/g).
When UACR was analyzed as a continuous variable, every double of increased UACR, the OR for LVH was 1.511 (95% CI: 1.047–2.180, P=0.028).
Overall, UACR below 30 mg/g is associated with LVH in patients with T2DM.
The optimal cutoff value of UACR for identifying LVH in diabetes is 10 mg/g.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xie, Xiangkun& Peng, Zhengliang& Li, Hanlin& Li, Dan& Tu, Yan& Bai, Yujia…[et al.]. 2020. Association of Urine AlbuminCreatinine Ratio below 30 mgg and Left Ventricular Hypertrophy in Patients with Type 2 Diabetes. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134604
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xie, Xiangkun…[et al.]. Association of Urine AlbuminCreatinine Ratio below 30 mgg and Left Ventricular Hypertrophy in Patients with Type 2 Diabetes. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1134604
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xie, Xiangkun& Peng, Zhengliang& Li, Hanlin& Li, Dan& Tu, Yan& Bai, Yujia…[et al.]. Association of Urine AlbuminCreatinine Ratio below 30 mgg and Left Ventricular Hypertrophy in Patients with Type 2 Diabetes. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134604
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1134604
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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