Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil
المؤلفون المشاركون
Ourique, A. F.
de Godoi, Samantha Nunes
Quatrin, Priscilla Maciel
Sagrillo, Michele Rorato
Nascimento, Kátia
Klein, Bruna
Santos, Roberto Christ Vianna
Wagner, Roger
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Essential oil of Eucalyptus globulus presents several pharmacological properties.
However, their therapeutic efficacy may be affected by limitations due to several conditions, rendering it difficult to obtain stable and effective pharmaceutical formulations.
The use of nanotechnology is an alternative to improve their characteristics aiming to ensure their stability and effectiveness.
Furthermore, studies about the possible toxic effects of nanostructures are necessary to evaluate safety when the formulation comes into contact with human cells.
Hence, in this paper, we evaluate for the first time the stability and in vitro cytogenotoxicity of nanoemulsions containing Eucalyptus globulus in peripheral blood mononuclear cells.
As a result, the stability study found that the best condition for storage up to 90 days was refrigeration (4°C); it was the condition that best preserved the nanometric features.
The content of the major compounds of oil was maintained after nanoencapsulation and preserved over time.
In tests to evaluate the safety of this formulation, we can conclude that, at a low concentration (approximately 0.1%), Eucalyptus globulus nanoemulsion did not cause toxicity in peripheral blood mononuclear cells and also showed a protective effect in cells against possible damage when compared to oil in free form.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
de Godoi, Samantha Nunes& Quatrin, Priscilla Maciel& Sagrillo, Michele Rorato& Nascimento, Kátia& Wagner, Roger& Klein, Bruna…[et al.]. 2017. Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1135077
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
de Godoi, Samantha Nunes…[et al.]. Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1135077
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
de Godoi, Samantha Nunes& Quatrin, Priscilla Maciel& Sagrillo, Michele Rorato& Nascimento, Kátia& Wagner, Roger& Klein, Bruna…[et al.]. Evaluation of Stability and In Vitro Security of Nanoemulsions Containing Eucalyptus globulus Oil. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1135077
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1135077
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر