Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic StrokeTransient Ischemic Attack
المؤلفون المشاركون
Fang, Qi
Kong, Yan
Cai, Xiuying
Zhang, Lulu
Hu, Xiaowei
Zhu, Juehua
Wang, Hui
Diao, Shanshan
Zhao, Hongru
Jiang, Jianhua
Wang, Dapeng
Zhang, Quanquan
Qin, Yiren
Yue, Wei
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-24
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
The correlation between platelet function and recurrent ischemic stroke or TIA remains uncertain.
Objective.
To investigate two inductive agents to detect platelet functions and assess associations with recurrent ischemic stroke/TIA.
Method.
The study included 738 ischemic stroke/TIA patients.
On days 0, 3, and 9 after antiplatelet therapy, platelet function tests were determined by maximum aggregation rate (MAR) using a PL-11 platelet function analyzer and phase matching reagents.
Two induction agents were used: arachidonic acid (AA) and adenosine diphosphate (ADP).
At 3-month follow-up, recurrence of stroke/TIA was recorded.
Result.
Cut-off values of adequate platelet function inhibition were MARADP < 35% and MARAA < 35%.
Data showed that antiplatelet therapy could reduce the maximum aggregation rate.
More importantly, adequate platelet function inhibition of either MARADP or MARAA was not associated with the recurrence of stroke/TIA, but adequate platelet function inhibition of not only MARADP but also MARAA predicts lower recurrence (0/121 (0.00%) versus 18/459 (3.92%), P = 0.0188).
Conclusion.
The platelet function tested by PL-11 demonstrated that adequate inhibition of both MARADP and MARAA could predict lower risk of ischemic stroke/TIA recurrence.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Lulu& Hu, Xiaowei& Zhu, Juehua& Cai, Xiuying& Kong, Yan& Wang, Hui…[et al.]. 2017. Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic StrokeTransient Ischemic Attack. BioMed Research International،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1136012
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Lulu…[et al.]. Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic StrokeTransient Ischemic Attack. BioMed Research International No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1136012
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Lulu& Hu, Xiaowei& Zhu, Juehua& Cai, Xiuying& Kong, Yan& Wang, Hui…[et al.]. Adequate Platelet Function Inhibition Confirmed by Two Inductive Agents Predicts Lower Recurrence of Ischemic StrokeTransient Ischemic Attack. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1136012
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136012
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر