The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”

المؤلفون المشاركون

Wang, Yi-Qin
Qian, Peng
Hao, Yiming
Yuan, Xue
Bai, Guanfeng

المصدر

BioMed Research International

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-06-21

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الطب البشري

الملخص EN

Aim.

To analyze the serum metabolites in patients with coronary heart disease (CHD) showing dampness syndrome and patients with chronic renal failure (CRF) showing dampness syndrome and to seek the substance that serves as the underlying basis of dampness syndrome in “same syndromes in different diseases.” Methods.

Metabolic spectrum by GC-MS was performed using serum samples from 29 patients with CHD showing dampness syndrome and 32 patients with CRF showing dampness syndrome.

The principal component analysis and statistical analysis of partial least squares were performed to detect the metabolites with different levels of expression in patients with CHD and CRF.

Furthermore, by comparing the VIP value and data mining in METLIN and HMDB, we identified the common metabolites in both patient groups.

Results.

(1) Ten differential metabolites were found in patients with CHD showing dampness syndrome when compared to healthy subjects.

Meanwhile, nine differential metabolites were found in patients with CRF showing dampness syndrome when compared to healthy subjects.

(2) There were 9 differential metabolites identified when the serum metabolites of the CHD patients with dampness syndrome were compared to those of CRF patients with dampness syndrome.

There were 4 common metabolites found in the serums of both patient groups.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Hao, Yiming& Yuan, Xue& Qian, Peng& Bai, Guanfeng& Wang, Yi-Qin. 2017. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1136418

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Hao, Yiming…[et al.]. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1136418

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Hao, Yiming& Yuan, Xue& Qian, Peng& Bai, Guanfeng& Wang, Yi-Qin. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1136418

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1136418