The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”
Joint Authors
Wang, Yi-Qin
Qian, Peng
Hao, Yiming
Yuan, Xue
Bai, Guanfeng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Aim.
To analyze the serum metabolites in patients with coronary heart disease (CHD) showing dampness syndrome and patients with chronic renal failure (CRF) showing dampness syndrome and to seek the substance that serves as the underlying basis of dampness syndrome in “same syndromes in different diseases.” Methods.
Metabolic spectrum by GC-MS was performed using serum samples from 29 patients with CHD showing dampness syndrome and 32 patients with CRF showing dampness syndrome.
The principal component analysis and statistical analysis of partial least squares were performed to detect the metabolites with different levels of expression in patients with CHD and CRF.
Furthermore, by comparing the VIP value and data mining in METLIN and HMDB, we identified the common metabolites in both patient groups.
Results.
(1) Ten differential metabolites were found in patients with CHD showing dampness syndrome when compared to healthy subjects.
Meanwhile, nine differential metabolites were found in patients with CRF showing dampness syndrome when compared to healthy subjects.
(2) There were 9 differential metabolites identified when the serum metabolites of the CHD patients with dampness syndrome were compared to those of CRF patients with dampness syndrome.
There were 4 common metabolites found in the serums of both patient groups.
American Psychological Association (APA)
Hao, Yiming& Yuan, Xue& Qian, Peng& Bai, Guanfeng& Wang, Yi-Qin. 2017. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1136418
Modern Language Association (MLA)
Hao, Yiming…[et al.]. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1136418
American Medical Association (AMA)
Hao, Yiming& Yuan, Xue& Qian, Peng& Bai, Guanfeng& Wang, Yi-Qin. The Serum Analysis of Dampness Syndrome in Patients with Coronary Heart Disease and Chronic Renal Failure Based on the Theory of “Same Syndromes in Different Diseases”. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1136418
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1136418