![](/images/graphics-bg.png)
Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia
المؤلفون المشاركون
Saito, Taku
Inagawa, Yuta
Komeno, Yukiko
Saito, Satoshi
Maenohara, Yuji
Yamagishi, Tetsuro
Kawashima, Hiroyuki
Abe, Keiko
Iihara, Kuniko
Hatada, Yasumasa
Ryu, Tomiko
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
A 34-year-old woman was diagnosed with acute promyelocytic leukemia.
Chemotherapy was administered following the JALSG APL204 protocol.
Induction therapy with all-trans retinoic acid resulted in complete remission on day 49.
She developed coccygeal pain from day 18, which spread to the spine and cheekbones and lasted 5 weeks.
She had similar bone pain on days 7–10 of the first consolidation therapy and on days 4–12 of the second consolidation therapy.
Oral loxoprofen was prescribed for pain relief.
On day 33 of the third consolidation, white blood cell and neutrophil counts were 320/μL and 20/μL, respectively.
After she developed epigastralgia and hematemesis, she developed septic shock.
Gastroendoscopy revealed markedly thickened folds and diffusely damaged mucosa with blood oozing.
Computed tomography revealed thickened walls of the antrum and the pylorus.
Despite emergency treatments, she died.
Bacterial culture of the gastric fluid yielded Enterobacter cloacae and enterococci growth.
Collectively, she was diagnosed with phlegmonous gastritis.
Retrospective examination of serial bone marrow biopsy specimens demonstrated progressive bone marrow fibrosis, which may have caused prolonged myelosuppression.
Thus, evaluation of bone marrow fibrosis by bone marrow biopsy after each treatment cycle might serve as a predictor of persistent myelosuppression induced by chemotherapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Inagawa, Yuta& Komeno, Yukiko& Saito, Satoshi& Maenohara, Yuji& Yamagishi, Tetsuro& Kawashima, Hiroyuki…[et al.]. 2019. Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia. Case Reports in Hematology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1136432
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Inagawa, Yuta…[et al.]. Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia. Case Reports in Hematology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1136432
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Inagawa, Yuta& Komeno, Yukiko& Saito, Satoshi& Maenohara, Yuji& Yamagishi, Tetsuro& Kawashima, Hiroyuki…[et al.]. Prolonged Myelosuppression due to Progressive Bone Marrow Fibrosis in a Patient with Acute Promyelocytic Leukemia. Case Reports in Hematology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1136432
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136432
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)