An Antibacterial Strategy of Mg-Cu Bone Grafting in Infection-Mediated Periodontics
المؤلفون المشاركون
Pan, Yaping
Zhao, Xue
Wan, Peng
Wang, Hongyan
Zhang, Shuwei
Liu, Jingbo
Chang, Chunrong
Yang, Ke
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Periodontal diseases are mainly the results of infections and inflammation of the gum and bone that surround and support the teeth.
In this study, the alveolar bone destruction in periodontitis is hypothesized to be treated with novel Mg-Cu alloy grafts due to their antimicrobial and osteopromotive properties.
In order to study this new strategy using Mg-Cu alloy grafts as a periodontal bone substitute, the in vitro degradation and antibacterial performance were examined.
The pH variation and Mg2+ and Cu2+ release of Mg-Cu alloy extracts were measured.
Porphyromonas gingivalis (P.
gingivalis) and Aggregatibacter actinomycetemcomitans (A.
actinomycetemcomitans), two common bacteria associated with periodontal disease, were cultured in Mg-Cu alloy extracts, and bacterial survival rate was evaluated.
The changes of bacterial biofilm and its structure were revealed by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM), respectively.
The results showed that the Mg-Cu alloy could significantly decrease the survival rates of both P.
gingivalis and A.
actinomycetemcomitans.
Furthermore, the bacterial biofilms were completely destroyed in Mg-Cu alloy extracts, and the bacterial cell membranes were damaged, finally leading to bacterial apoptosis.
These results indicate that the Mg-Cu alloy can effectively eliminate periodontal pathogens, and the use of Mg-Cu in periodontal bone grafts has a great potential to prevent infections after periodontal surgery.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhao, Xue& Wan, Peng& Wang, Hongyan& Zhang, Shuwei& Liu, Jingbo& Chang, Chunrong…[et al.]. 2020. An Antibacterial Strategy of Mg-Cu Bone Grafting in Infection-Mediated Periodontics. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136730
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhao, Xue…[et al.]. An Antibacterial Strategy of Mg-Cu Bone Grafting in Infection-Mediated Periodontics. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1136730
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhao, Xue& Wan, Peng& Wang, Hongyan& Zhang, Shuwei& Liu, Jingbo& Chang, Chunrong…[et al.]. An Antibacterial Strategy of Mg-Cu Bone Grafting in Infection-Mediated Periodontics. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1136730
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1136730
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر