Application of a New Type of Natural Calcined Bone Repair Material Combined with Concentrated Growth Factors in Bone Regeneration in Rabbit Critical-Sized Calvarial Defect
المؤلفون المشاركون
Liu, Zhenxing
Wang, Xiaoyang
Tong, Shuqing
Huang, Shengyun
Zhang, Dongsheng
Ma, Li
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
This study is aimed at investigating bone regeneration in critical-sized defects in rabbit calvarium using a novel nano- (n-) hydroxyapatite hybrid scaffold with concentrated growth factors (CGFs).
Methods.
Twenty-four male adult rabbits were chosen to establish a critical-sized bone defect model and randomly divided into two groups.
Two defects of 15 mm diameter each were created in the parietal bone of each animal.
Group A had n-hydroxyapatite hybrid scaffold placed in the experimental defect on the right, and the left defect was unfilled as blank.
Group B had hydroxyapatite hybrid scaffold mixed with CGF placed in the right defect and CGF on the left.
Six animals in each group were sacrificed after 6 and 12 weeks.
Cone-beam computed tomography system scanning and hematoxylin and eosin (HE) staining were used to detect osteogenesis within the defects.
Results.
The treatment with n-hydroxyapatite hybrid scaffold along with CGF resulted in a significantly higher amount of new bone at 6 and 12 weeks compared to the treatment with CGF alone and the controls.
No apparent inflammation and foreign body reaction were observed through HE staining.
Conclusions.
The new synthesized n-hydroxyapatite hybrid scaffold and CGF can be applied for bone defect regeneration to promote the process to a certain extent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Xiaoyang& Tong, Shuqing& Huang, Shengyun& Ma, Li& Liu, Zhenxing& Zhang, Dongsheng. 2020. Application of a New Type of Natural Calcined Bone Repair Material Combined with Concentrated Growth Factors in Bone Regeneration in Rabbit Critical-Sized Calvarial Defect. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1137668
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Xiaoyang…[et al.]. Application of a New Type of Natural Calcined Bone Repair Material Combined with Concentrated Growth Factors in Bone Regeneration in Rabbit Critical-Sized Calvarial Defect. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1137668
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Xiaoyang& Tong, Shuqing& Huang, Shengyun& Ma, Li& Liu, Zhenxing& Zhang, Dongsheng. Application of a New Type of Natural Calcined Bone Repair Material Combined with Concentrated Growth Factors in Bone Regeneration in Rabbit Critical-Sized Calvarial Defect. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1137668
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137668
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر