Association of the Differences in Average Glandular Dose with Breast Cancer Risk
المؤلفون المشاركون
He, Zilong
Lin, Xiaojia
Ma, Le
Cai, Yuxing
Chen, Weiguo
Qin, Genggeng
Zeng, Hui
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives.
To compare the differences in normalized average glandular dose (NAGD) between the breasts of healthy subjects and those of cancer patients and to determine if the NAGD difference is associated with breast cancer risk and improves breast cancer classification.
Materials and Methods.
Craniocaudal view and mediolateral view full-field digital mammography (FFDM) images were obtained from 1682 healthy subjects whose breasts were categorized as Breast Imaging-Reporting and Data System (BI-RADS) I or II and from 811 biopsy-confirmed unilateral breast cancer patients whose breasts on the contralateral side were category I or II.
Both populations were randomized into training and test sets.
Multivariate logistic regression analysis was used to build the breast cancer risk assessment model, and the area under the receiver operating characteristic curve (Az) was used to evaluate the model.
Twenty-two breast cancer patients who were originally categorized as BI-RADS I or II for both breasts, but were diagnosed with unilateral biopsy-confirmed breast cancer subsequently, were included to validate the model.
Results.
The NAGD differences in both FFDM images between tumor-bearing breasts and the healthy breasts of patients were significantly higher than those in healthy subjects (P<0.001).
The model with NAGD differences had a higher Az value than the model without NAGD differences.
While there was no NAGD differences between originally healthy breasts of breast cancer patients, significant NAGD differences between now tumor-bearing breasts and the then previously healthy breasts were found in both FFDM images.
Conclusions.
NAGD differences between both breasts can be included in the breast cancer risk assessment model to evaluate breast cancer risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ma, Le& Cai, Yuxing& Lin, Xiaojia& He, Zilong& Zeng, Hui& Chen, Weiguo…[et al.]. 2020. Association of the Differences in Average Glandular Dose with Breast Cancer Risk. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137879
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ma, Le…[et al.]. Association of the Differences in Average Glandular Dose with Breast Cancer Risk. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1137879
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ma, Le& Cai, Yuxing& Lin, Xiaojia& He, Zilong& Zeng, Hui& Chen, Weiguo…[et al.]. Association of the Differences in Average Glandular Dose with Breast Cancer Risk. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1137879
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137879
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر