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Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice
المؤلفون المشاركون
Zhong, Zhangfeng
Wu, Haiyou
Lin, Sien
Qiu, Chuqun
Xie, Peitao
Lv, Simin
Cui, Liao
Wu, Tie
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-19
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The level of sun ultraviolet ray reaching the surface of the earth is increasing severely due to the rapid development of the society and environmental destruction.
Excessive exposure to ultraviolet radiation causes skin damage and photoaging.
Therefore, it is emerged to develop effective sunscreen to prevent ultraviolet-induced skin damage.
This study was aimed at investigating the effects of Coenzyme Q10 (CoQ10) sunscreen on the prevention of ultraviolet B radiation- (UVB-) induced mouse skin damage.
Three-month-old female mice were used, and they were randomly divided into four groups: control, model, CoQ10, and titanium dioxide (TiO2; positive control) groups.
Our results showed that body weight, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities, and DNA (cytosine-5)-methyltransferase 1 (DNMT1) protein expression were significantly decreased, while malondialdehyde (MDA) activity and metalloproteinase-1 (MMP-1) level were increased in UVB-treated mice.
Besides, the stratum corneum was shed from the skin surface in the model group compared with the control group.
In contrast, CoQ10 sunscreen prevented from UVB-induced skin damage, as well as reversing SOD, GSH-Px, and MDA activities, and MMP-1 and DNMT1 levels.
Taken together, the current study provided further evidence on the prevention of UVB-induced skin damage by CoQ10 and its underlying mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Haiyou& Zhong, Zhangfeng& Lin, Sien& Qiu, Chuqun& Xie, Peitao& Lv, Simin…[et al.]. 2020. Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1137926
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Haiyou…[et al.]. Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1137926
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Haiyou& Zhong, Zhangfeng& Lin, Sien& Qiu, Chuqun& Xie, Peitao& Lv, Simin…[et al.]. Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1137926
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137926
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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