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The Role of Interleukin-17, Interleukin-23, and Transforming Growth Factor-β in Pregnancy Complicated by Placental Insufficiency
المؤلفون المشاركون
Bojarska-Junak, Agnieszka
Darmochwal-Kolarz, Dorota
Kolarz, Bogdan
Oleszczuk, Jan
Michalak, Magdalena
Przegalinska-Kalamucka, Monika
Sliwa, Dariusz
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aim.
The aim of the study was to evaluate the role of Interleukin-17 (IL-17), Interleukin-23 (IL-23), and transforming growth factor-β (TGF-β) in pregnancy complicated by placental insufficiency and in normal pregnancy.
Material and Methods.
The study comprised 34 patients with pregnancy complicated by fetal growth restriction (FGR) associated with preeclampsia (PE), as well as 35 healthy pregnant women.
The concentrations of IL-17, IL-23, and TGF-β in sera from maternal peripheral blood were determined by an immunoenzymatic assay.
Results.
There were higher concentrations of IL-17 in the study group when compared to the controls.
In the group of patients with placental insufficiency, the levels of IL-17 positively correlated with systolic blood pressure (R=0.42, p<0.01).
The study obtained comparable concentrations of IL-23 in both studied groups.
The concentrations of TGF-β were significantly lower in pregnancy complicated by the insufficiency of placenta when compared to the controls.
Conclusions.
It seems possible that the increased concentrations of IL-17 and the deficiency of TGF-β in pregnancy complicated by FGR and PE can be responsible for the activation of inflammatory response observed in PE cases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Darmochwal-Kolarz, Dorota& Michalak, Magdalena& Kolarz, Bogdan& Przegalinska-Kalamucka, Monika& Bojarska-Junak, Agnieszka& Sliwa, Dariusz…[et al.]. 2017. The Role of Interleukin-17, Interleukin-23, and Transforming Growth Factor-β in Pregnancy Complicated by Placental Insufficiency. BioMed Research International،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1138276
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Darmochwal-Kolarz, Dorota…[et al.]. The Role of Interleukin-17, Interleukin-23, and Transforming Growth Factor-β in Pregnancy Complicated by Placental Insufficiency. BioMed Research International No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1138276
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Darmochwal-Kolarz, Dorota& Michalak, Magdalena& Kolarz, Bogdan& Przegalinska-Kalamucka, Monika& Bojarska-Junak, Agnieszka& Sliwa, Dariusz…[et al.]. The Role of Interleukin-17, Interleukin-23, and Transforming Growth Factor-β in Pregnancy Complicated by Placental Insufficiency. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1138276
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138276
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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