Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome
المؤلفون المشاركون
Tang, Liang
Fang, Zhen-fei
Hu, Xin-qun
Tai, Shi
Li, Xuping
Zhu, Zhaowei
Yang, Hui
Fu, Liyao
Zhou, Shenghua
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-22
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Hyperuricemia is a risk factor for cardiovascular diseases, but the impact of hyperuricemia and sex-related disparities is not fully clear in elderly patients with acute coronary syndrome (ACS).
Objective.
To investigate the association between hyperuricemia and 1-year all-cause mortality in elderly patients with ACS.
Methods.
This retrospective cohort study included 711 consecutive ACS patients aged ≥75 years, hospitalized in our center between January 2013 and December 2017.
Serum uric acid (sUA), in-hospital events, and 1-year follow-up were analyzed.
Multivariable logistic regression models were used to explore the risk factors for in-hospital events and 1-year all-cause mortality.
Results.
sUA levels were higher in males than in females (381.4 ± 110.1 vs.
349.3 ± 119.1 μmol/l, P<0.001).
Prevalence of hypertension (80.5% vs.
72.6%, P=0.020), atrial fibrillation (16.2% vs.
9.5%, P=0.008), and severe heart failure (61.0% vs.
44.2%, P<0.001) were higher in patients with hyperuricemia than in patients with normal sUA.
During the 1-year follow-up, 135 patients died (19.0%); all-cause mortality was higher in patients with hyperuricemia than in patients with normal sUA (23.1% vs.
16.7%, P=0.039).
Hyperuricemia is related to in-hospital ventricular tachycardia and 1-year all-cause mortality (OR = 1.799, 95% CI 1.050–3.081, P=0.033; OR = 1.512, 95% CI 1.028–2.225, P=0.036, respectively).
Multivariable regression analysis models showed that hyperuricemia was an independent risk factor of 1-year all-cause mortality in women (OR = 2.539, 95% CI 1.001–6.453, P=0.050), but not in men (OR = 0.931, 95% CI 0.466–1.858, P=0.839) after adjustment for confounding variables.
Conclusions.
Hyperuricemia is an independent risk factor for 1-year all-cause mortality in elderly female patients with ACS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tai, Shi& Li, Xuping& Zhu, Zhaowei& Tang, Liang& Yang, Hui& Fu, Liyao…[et al.]. 2020. Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome. Cardiovascular Therapeutics،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1138586
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tai, Shi…[et al.]. Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome. Cardiovascular Therapeutics No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1138586
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tai, Shi& Li, Xuping& Zhu, Zhaowei& Tang, Liang& Yang, Hui& Fu, Liyao…[et al.]. Hyperuricemia is a Risk Factor for One-Year Overall Survival in Elderly Female Patients with Acute Coronary Syndrome. Cardiovascular Therapeutics. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1138586
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138586
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر