![](/images/graphics-bg.png)
Neutrophil-to-Lymphocyte Ratio Is a Potential Prognostic Biomarker in Patients with Ovarian Cancer: A Meta-Analysis
المؤلفون المشاركون
Chen, Shubo
Zhang, Liu
Yan, Guangyue
Cheng, Sijin
Fathy, Abdel Hamid
Yan, Nana
Zhao, Yongzhao
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-26
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Aims.
Plenty of studies were conducted to explore the prognostic significance of neutrophil-to-lymphocyte ratio (NLR) in ovarian cancer with contradictory results.
This study aims to summarize the prognostic significance of NLR in patients with ovarian cancer.
Methods.
A literature search in PubMed, Cochrane Library, and Embase was conducted.
The endpoints were progression-free survival (PFS) and overall survival (OS).
Results.
Eleven studies involving a total of 2,892 patients were identified.
The results indicated that patients with high NLR had shorter PFS compared to patients with low NLR in ovarian cancer (HR = 1.55, 95% CI = 1.15–2.08, p=0.004, and I2=61%).
Similarly, high NLR was related to shorter OS (HR = 1.51, 95% CI = 1.03–2.23, p=0.04, and I2=85%).
Moreover, high NLR was significantly associated with shorter PFS when the NLR cut-off was less than 3.3 (p=0.03) or when treatment is operation (p=0.002).
In addition, high NLR was distinctly related to worse OS in Asian people (p = 0.04) or operation (p = 0.04).
Conclusion.
High NLR was associated with shorter PFS and shorter OS in ovarian cancer.
NLR is potentially a promising prognostic biomarker in patients with ovarian cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Shubo& Zhang, Liu& Yan, Guangyue& Cheng, Sijin& Fathy, Abdel Hamid& Yan, Nana…[et al.]. 2017. Neutrophil-to-Lymphocyte Ratio Is a Potential Prognostic Biomarker in Patients with Ovarian Cancer: A Meta-Analysis. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138810
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Shubo…[et al.]. Neutrophil-to-Lymphocyte Ratio Is a Potential Prognostic Biomarker in Patients with Ovarian Cancer: A Meta-Analysis. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1138810
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Shubo& Zhang, Liu& Yan, Guangyue& Cheng, Sijin& Fathy, Abdel Hamid& Yan, Nana…[et al.]. Neutrophil-to-Lymphocyte Ratio Is a Potential Prognostic Biomarker in Patients with Ovarian Cancer: A Meta-Analysis. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138810
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138810
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)