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Association between Fluorescent Advanced Glycation End-Products and Vascular Complications in Type 2 Diabetic Patients
المؤلفون المشاركون
Bourdon, Emmanuel
Dubourg, Alexis Guerin
Rondeau, Philippe
Cournot, Maxime
Planesse, Cynthia
Debussche, Xavier
Meilhac, Olivier
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-06
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objectives.
Diabetes is a major health problem associated with hyperglycemia and chronically increased oxidative stress and enhanced formation of advanced glycation end-products (AGEs).
The aim of this study was to determine whether oxidative plasma biomarkers in diabetic patients could be evidenced and associated with vascular complications.
Methods.
Oxidative stress biomarkers such as thiols, ischemia-modified albumin (IMA), glycated albumin (GA), fructosamine, and AGEs were measured in 75 patients with poorly controlled type 2 diabetes (HbA1c > 7.5%) with (44) or without (31) vascular disease and in 31 nondiabetic controls.
Results.
Most biomarkers of oxidation and glycation were significantly increased in diabetic patients in comparison with nondiabetics.
Fructosamines, GA, IMA, and AGEs were positively correlated and levels of fluorescent AGEs were significantly increased in the plasma from patients presenting vascular complication.
Conclusions.
These results bring new evidence for the potential interest of glycated albumin, oxidative stress, and glycoxidation parameters in the monitoring of type 2 diabetic patients.
Furthermore, it emphasizes fluorescent AGEs as a putative indicator for vascular event prediction in diabetic patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dubourg, Alexis Guerin& Cournot, Maxime& Planesse, Cynthia& Debussche, Xavier& Meilhac, Olivier& Rondeau, Philippe…[et al.]. 2017. Association between Fluorescent Advanced Glycation End-Products and Vascular Complications in Type 2 Diabetic Patients. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1138844
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dubourg, Alexis Guerin…[et al.]. Association between Fluorescent Advanced Glycation End-Products and Vascular Complications in Type 2 Diabetic Patients. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1138844
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dubourg, Alexis Guerin& Cournot, Maxime& Planesse, Cynthia& Debussche, Xavier& Meilhac, Olivier& Rondeau, Philippe…[et al.]. Association between Fluorescent Advanced Glycation End-Products and Vascular Complications in Type 2 Diabetic Patients. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1138844
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138844
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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