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Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department
المؤلفون المشاركون
Swain, Mark G.
Ragan, Kelsey
Pandya, Anjali
Holotnak, Tristan
Koger, Katrina
Collins, Neil
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-02-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Approximately 0.7% of the Canadian population is infected with hepatitis C virus (HCV), and many individuals are unaware of their infection.
Our objectives were to utilize an emergency department (ED) based point-of-care (POC) HCV screening test to describe our local population and estimate the proportion of high-risk patients in our population with undiagnosed HCV.
Methods.
A convenience sample of medically stable patients (≥18 years) presenting to a community ED in Calgary, AB, between April and July 2018 underwent rapid clinical screening for HCV risk factors, including history of injection drug use, healthcare in endemic countries, and other recognized criteria.
High-risk patients were offered POC HCV testing.
Antibody-positive patients underwent HCV-RNA testing and were linked to hepatology care.
The primary outcome was the proportion of new HCV diagnoses in the high-risk population.
Results.
Of the 999 patients screened by survey, 247 patients (24.7%) were high-risk and eligible for testing.
Of these, 123 (49.8%) were from HCV-endemic countries, while 63 (25.5%) and 31 (12.6%) patients endorsed a history of incarceration and intravenous drug use (IVDU), respectively.
A total of 144 (58.3%) eligible patients agreed to testing.
Of these, 6 patients were POC-positive (4.2%, CI 0.9–7.4%); all 6 had antibodies detected on confirmatory lab testing and 4 had detectable HCV-RNA viral loads in follow-up.
Notably, 103 (41.7%) patients declined POC testing.
Interpretation.
Among 144 high-risk patients who agreed to testing, the rate of undiagnosed HCV infection was 4.2%, and the rate of undiagnosed HCV infection with detectable viral load was 2.8%.
Many patients with high-risk clinical criteria refused POC testing.
It is unknown if tested and untested groups have the same disease prevalence.
This study shows that ED HCV screening is feasible and that a small number of previously undiagnosed patients can be identified and linked to potentially life-changing care.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ragan, Kelsey& Pandya, Anjali& Holotnak, Tristan& Koger, Katrina& Collins, Neil& Swain, Mark G.. 2020. Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139019
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ragan, Kelsey…[et al.]. Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1139019
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ragan, Kelsey& Pandya, Anjali& Holotnak, Tristan& Koger, Katrina& Collins, Neil& Swain, Mark G.. Hepatitis C Virus Screening of High-Risk Patients in a Canadian Emergency Department. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139019
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139019
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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